PR Ascorbic Acid Injection 500 mg (Ascorbic Acid)

Adult administration

As ascorbic acid, 50 to 1,000 mg should be administered by subcutaneous, intramuscular, or intravenous injection divided into 1 to several doses per day. Adjust according to age and symptoms.

This medication is an ampule injection and should be cut very carefully to avoid glass shards being mixed. Extra caution is needed, especially when used on children or elderly patients. It contains sodium bisulfite which can cause severe allergic reactions or asthma attacks in patients with sulfite allergies or asthma, so it must be administered cautiously. It should not be administered to patients with hypersensitivity to this drug or with certain diseases, such as idiopathic hyperoxaluria, Mediterranean anemia, gout, cystinuria, G6PD deficiency, and patients with kidney stones. Side effects such as nausea, vomiting, diarrhea, abdominal cramps, fatigue, facial flushing, headache, and insomnia may occur during administration. High doses may increase the risk of diarrhea or kidney stones, and diuretic effects may also occur. Excessive doses can cause problems in the kidneys, so caution is needed. This medication is generally taken orally but can be administered as an injection if necessary. Interactions may occur when taken with certain medications, so caution is advised, especially when combined with salicylates, aspirin, iron supplements, anticonvulsants, and oral contraceptives. During pregnancy, it should only be administered when necessary, as safety for the fetus has not been established, and high doses should be avoided. Caution is also needed during breastfeeding, but no significant risks have been reported at regular doses. This drug may affect the results of urine sugar tests or hematuria tests, so it should be taken into account during examinations. In case of overdose, symptoms such as diarrhea or kidney stones may occur, and use should be immediately stopped and appropriate treatment sought if symptoms develop. Injection may cause pain at the injection site, particularly when administered to infants or children, so care should be taken to avoid neural areas and not to repeat the injection site. If the injection speed is too fast, dizziness or phlebitis may occur, so it is advisable to inject slowly. Finally, this medication should be stored out of the reach of children, protected from direct sunlight, and kept in a dry place. It should also be stored in its original container to prevent quality degradation or misuse.

Serious side effects

Asthma attacks, hemolysis.

Mild side effects

Nausea, vomiting, diarrhea, abdominal cramps, fatigue, flushing, headache, insomnia, diuretic effects, transient mild pain at the injection site, phlebitis, dizziness, fainting.

This medication is sensitive to light, so it should be stored in an opaque container. Additionally, to keep the drug fresh, it should be stored at a refrigerated temperature between 2 and 8 degrees Celsius.

Appearance

A transparent colorless or pale yellow injection solution contained in a brown vial.

Package unit

10 vials/box [20 mL/vial], 10 vials/box [50 mL/vial]