BIDAGLIMET Tablet 50/850 mg (Vildagliptin, Metformin)

Adult dose

In the treatment of type 2 diabetes, vildagliptin is administered up to a maximum of 100 mg and metformin up to 2000 mg, and individualization based on efficacy and tolerability is necessary. This medication is generally administered with meals or immediately after meals to reduce gastrointestinal adverse reactions caused by metformin. 1. For patients with no previous diabetes medication experience and insufficient blood sugar control with monotherapy:

This medication can cause severe lactic acidosis or hypoglycemia, and should not be used, particularly in patients with moderate to severe renal impairment or those with heart failure. Discontinue this medication at least 48 hours before any examination that uses iodinated contrast agents, and resume only after confirming normal renal function post-examination. Patients with allergies to this medication, those with type 1 diabetes, acute metabolic acidosis patients, or women who are pregnant or breastfeeding should not use this medication. Irregular meals, intense physical activity, or taking other medications may increase the risk of hypoglycemia and lactic acidosis, so caution is required. During treatment, liver function and renal function should be monitored regularly, and if abnormalities are found, consult a physician immediately. If symptoms of acute pancreatitis occur, stop taking the medication immediately and seek medical advice, and be cautious in cases with a history of acute pancreatitis. Excessive alcohol consumption increases the risk of lactic acidosis, so avoid alcohol while taking this medication. Elderly patients are at higher risk of renal function decline, thus dosage adjustments and regular renal function tests are necessary. If symptoms of hypoglycemia occur, consume sugar immediately, and if severe, inform healthcare personnel. Patients scheduled for surgery should stop taking this medication 48 hours prior to surgery and only resume once oral intake has recovered and renal function is confirmed normal post-surgery. This medication is not recommended for children and adolescents. In case of overdose, seek appropriate medical attention immediately; this medication can be removed through hemodialysis, so dialysis treatment may be necessary if required. If unusual symptoms such as blisters or ulcerations on the skin occur, inform the physician immediately and seek medical care. During treatment, regularly check blood sugar and hemoglobin A1c levels to verify treatment effectiveness and safety.

Serious side effects

Hives, angioedema, hepatitis, skin lesions (blisters, exfoliative skin lesions, bullous pemphigoid), pancreatitis, severe and disabling joint pain, jaundice, lactic acidosis, liver dysfunction, acute pancreatitis, severe lactic acidosis, severe allergic reactions

Mild side effects

• Headache
• dizziness
• tremor
• fatigue
• nausea
• gastroesophageal reflux
• diarrhea
• bloating
• chills
• decreased blood sugar

This medication is sensitive to air and moisture; therefore, it must be stored in a tightly closed container. Maintain a storage temperature between 1 to 30 degrees Celsius at room temperature, avoiding humid places.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle