EPIUM DUO Tablet 20/800 mg

Adult dose

Take this medication on an empty stomach at least 1 hour before meals. Swallow whole with at least half a cup of water. Do not take with any other beverages except water. Do not chew or crush. Treatment of gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: Take 40/800 mg once daily for 4 weeks. If symptoms persist or are not treated, continue for an additional 4 weeks. - Long-term maintenance therapy for patients with esophagitis

This medication should not be used in specific patients. For example, patients who have had allergic reactions or hypersensitivity to this medication or its ingredients, patients taking certain antiviral agents (atazanavir, nelfinavir, rilpivirine), nursing women, and patients with a history of myocardial infarction should not be administered this medication. Patients with poor liver function, kidney problems, the elderly, those with decreased cardiac or pulmonary function, patients with severe gastrointestinal ulcers, and those with electrolyte imbalances should use this medication cautiously. Patients who should particularly limit sodium intake need to be careful. This medication can cause various side effects. Gastrointestinal symptoms such as headache, dizziness, abdominal pain, diarrhea, nausea, and vomiting, as well as skin rashes, itching, hair loss, and rarely severe allergic reactions or skin diseases may occur. Blood abnormalities, muscle pain, nephritis, mental confusion, insomnia, etc., have also been reported. Rarely, electrolyte abnormalities such as hypomagnesemia, hypokalemia, and hypocalcemia may occur, necessitating regular testing during prolonged use. This medication suppresses gastric acid secretion, which may increase the risk of bacterial infections in the gastrointestinal tract. There is a higher risk of diarrhea caused by Clostridium difficile in hospitalized patients, so if diarrhea symptoms persist, consult a doctor. Long-term use of this medication may increase the risk of fractures, and patients at risk for osteoporosis are recommended to have regular bone density tests. This medication may interact with other drugs, so caution is needed when combined with anticoagulants, antiviral agents, anticonvulsants, antidepressants, etc. All medications being taken should be disclosed to a doctor or pharmacist. Data on the safety of this medication during pregnancy is limited, so pregnant women should consult a doctor before using it, and nursing mothers should avoid using this medication. In case of overdose, there is no specific antidote, so treatment should be symptomatic under a doctor's guidance. This medication should be stored out of reach of children, and transferring it to another container may compromise its quality, so caution is necessary.

Serious side effects

Hives, severe swelling (edema), angioedema, anaphylactic reaction/shock, skin peeling, pain in oral/ocular mucosa, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, eosinophilia with systemic symptoms drug reaction (DRESS syndrome), difficulty breathing, asthma exacerbation, respiratory abnormalities accompanying cough + fever, jaundice

Mild side effects

• Leukopenia
• thrombocytopenia
• agranulocytosis
• pancytopenia
• fever
• peripheral edema
• hyponatremia
• hypomagnesemia
• insomnia
• anxiety

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is advisable to keep it at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will help maintain its effectiveness.

Appearance

Pale pink rectangular film-coated tablet

Package unit

28 tablets (7 tablets/PTPX4)