Nexiu Duo Tablet 20/800 mg

Adult dose

This medication should be taken on an empty stomach at least 1 hour before meals. It should be swallowed whole with at least half a cup of water. Do not take with beverages other than water. Do not chew or crush the tablet. For the treatment of erosive reflux esophagitis: Administer 40/800 mg once daily for 4 weeks. If the treatment is ineffective or if symptoms persist, continue for an additional 4 weeks. For long-term maintenance therapy to prevent recurrence: 20/800 mg once daily.

This medication should not be administered to patients who have allergies or have experienced hypersensitivity reactions to this drug or its components. It is also contraindicated for patients taking specific antiviral medications such as atazanavir, nelfinavir, and rilpivirine due to risks of side effects or interactions. Women who are breastfeeding should avoid taking this medication. Caution is required for patients with a history of myocardial infarction or heart-related conditions. Patients with liver or kidney dysfunction, elderly patients, those with severe gastrointestinal ulcers, and patients with cardiopulmonary dysfunction should use this medication with caution. Patients requiring electrolyte imbalance management or sodium intake restriction should also exercise caution. One of the active ingredients in this medication inhibits gastric acid secretion, which can result in various side effects such as headache, dizziness, dyspepsia, skin rash, and myalgia. In severe cases, abnormalities in blood, liver dysfunction, and severe skin reactions may occur, so if any unusual symptoms arise, immediate consultation with medical staff is needed. Long-term use requires regular examinations and blood tests, and caution should be taken as the risk of gastrointestinal bacterial infections may increase, necessitating attention to symptoms like diarrhea. Additionally, this medication has many interactions with other drugs, so it is essential to inform medical staff about any other medications being taken. Caution is especially necessary when used with drugs affecting blood coagulation, antiviral drugs, and immunosuppressants. Women who are pregnant or planning to become pregnant should follow medical advice when using this medication, and those who are nursing should avoid it. In the case of overdose, there are no specific antidotes, so appropriate treatment should be provided depending on the symptoms, and it should be kept in a safe place out of reach of children.

Serious side effects

Angioedema, anaphylactic reactions, shock, urticaria, severe hypomagnesemia, microscopic colitis, jaundice, hepatitis, liver failure, encephalopathy, erythema multiforme, skin and mucous membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), severe edema, severe allergic reactions, severe skin adverse reactions, breathing difficulties

Mild side effects

• Leukopenia
• thrombocytopenia
• peripheral edema
• hyponatremia
• hypomagnesemia
• insomnia
• agitation
• mental confusion
• depression
• aggression

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is advisable to maintain the storage temperature between 1 to 30 degrees Celsius at room temperature.

Appearance

Pale pink, oblong film-coated tablet

Package unit

28 tablets (7 tablets/PTP x 4)