Donepezil 23 mg Tablets (Donepezil Hydrochloride Monohydrate)

Adult dose

This medication should be taken once daily, just before bedtime, and can be administered without regard to food. The initial recommended dose of Donepezil Hydrochloride is 5 mg, taken once daily. Normal state is reached after 15 days, and for 4 to 6 weeks, 5 mg should be administered. After evaluating the clinical response, the dose may be increased to 10 mg, but gastrointestinal adverse reactions should be monitored. For patients who have been taking 10 mg once daily for at least 3 months,

This medication contains Donepezil Hydrochloride Monohydrate as its active ingredient and is primarily used for the treatment of Alzheimer's disease symptoms. This medication should not be administered to certain patients. For example, people allergic to this medication or its components, pregnant women, or women who may become pregnant, and patients with genetic issues such as lactose intolerance should not take this medication. Patients with heart disease or heart conduction disorders should use this medication cautiously, as it may stimulate the vagus nerve and cause heart issues such as bradycardia or arrhythmias. Patients taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should also be careful, as this medication can increase gastric acid secretion and promote gastrointestinal motility, potentially worsening ulcer symptoms. Patients with a history of asthma or obstructive pulmonary disease may experience worsening symptoms when using this medication, so caution is advised. Patients with extrapyramidal disorders such as Parkinson's disease may have worsening symptoms due to this medication. This medication contains Yellow No. 4, so those allergic to this component should be cautious. A variety of adverse reactions may occur while taking this medication. For example, cardiovascular issues (bradycardia, heart block, myocardial infarction), gastrointestinal problems (gastric ulcer, gastrointestinal bleeding), liver function abnormalities, neurological symptoms (seizures, cerebral hemorrhage), and movement disorders have been reported. Additionally, common symptoms may include hallucinations, insomnia, dizziness, nausea, vomiting, diarrhea, loss of appetite, fatigue, headaches, and others. The frequency and intensity of adverse reactions may vary depending on the dosage of this medication, particularly at higher doses, where gastrointestinal symptoms such as nausea, vomiting, and diarrhea may occur more frequently. During treatment, the patient's condition should be regularly monitored, and immediate consultation with medical personnel should occur if any unusual symptoms appear. Pregnant or nursing women are advised not to use this medication and should make careful decisions after consulting with a physician if it is absolutely necessary. Safety for pediatric use has not yet been established, so children should not take this medication. This medication may interact with other drugs, so if there are any concomitant medications, it is essential to inform the doctor or pharmacist. Caution is especially necessary when used with medications affecting the heart, those affecting liver metabolism, and neuromuscular blocking agents. In case of overdose, severe symptoms such as nausea, vomiting, severe muscle weakness, and respiratory distress may occur, so immediate medical attention is required. This medication should be stored out of reach of children, and it is important to keep it in the original container without transferring it to another to maintain safety and quality.

Serious side effects

Syncope, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcer, perforated duodenal perforation, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, cerebral seizure, cerebral hemorrhage, cerebrovascular disorders, extrapyramidal disorders (motor dysfunction, ataxia, movement disorders, abnormal muscle tone, tremors, involuntary movements, gait disturbances, abnormal postures, speech disorders), neuroleptic malignant syndrome (stiffness, extreme rigidity, difficulty swallowing, empty

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headaches
• fatigue
• weakness
• insomnia
• dizziness
• drowsiness

This medication should be stored in a tightly sealed container that is well-ventilated. The recommended storage temperature is between 1°C and 30°C, maintaining room temperature. This helps maintain the effectiveness of the medication.

Appearance

Red, round, film-coated tablets that are convex on both sides

Package unit

30 tablets per bottle