Donepezil 23 mg Tablets (Donepezil Hydrochloride Monohydrate)

Adult dose

This medication should be taken once daily just before bedtime, and can be taken regardless of meals. The initial recommended dose of Donepezil Hydrochloride is 5 mg once daily. After administering 5 mg for 4 to 6 weeks, clinical response should be evaluated, and dosage may be increased to 10 mg. When increasing to 10 mg daily, caution should be exercised regarding gastrointestinal adverse reactions. Patients taking 10 mg once daily for a minimum of 3 months may receive 23 mg once daily.

This drug is used to improve symptoms of Alzheimer's type dementia with Donepezil Hydrochloride Monohydrate as its main component. This medication should not be administered to certain patients. For instance, it should be avoided by those who are allergic to this drug or its components, pregnant or nursing women, and patients with genetic issues such as lactose intolerance. Patients with heart disease or a history of peptic ulcers, asthma, or obstructive pulmonary disease, as well as those with extrapyramidal disorders such as Parkinson's disease, should take special caution when using this medication. This drug can cause serious side effects, such as bradycardia or arrhythmia, gastrointestinal bleeding, liver dysfunction, seizures, movement disorders, and respiratory distress; patients should notify their doctor immediately if any of these symptoms occur. Additionally, relatively common side effects such as nausea, vomiting, diarrhea, loss of appetite, dizziness, insomnia, headache, and fatigue may also occur and should be monitored. Particular caution is required for patients with pre-existing conditions such as heart disease, liver dysfunction, peptic ulcers, or asthma. Regular medical oversight and testing while on this medication is recommended. Pregnant or nursing women are advised against using this drug unless absolutely necessary and should consult a professional before making any decisions. This medication may interact with other drugs, particularly those affecting the heart, antibiotics, antidepressants, antipsychotics, and NSAIDs, so patients must inform their doctor or pharmacist when taking these medications together. Dizziness or fatigue may occur while driving or operating machinery, especially during the initial stages of usage or when dosage changes occur; therefore, caution is warranted. In case of overdose, severe symptoms such as severe nausea, vomiting, hypotension, bradycardia, and respiratory depression may appear, requiring an immediate visit to a medical facility. Antidotes such as atropine may be used. This drug is not recommended for use in children, and it should be stored out of reach of children in a safe place.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucous membranes, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough + fever, jaundice (yellowing of skin or eyes), profound lethargy, sudden and very severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urination

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• lethargy
• dizziness
• drowsiness
• insomnia

This medication should be stored in a closed container to prevent air or moisture from entering. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. Proper storage will help maintain the effectiveness of the medication for a longer time.

Appearance

Red, round, biconvex film-coated tablet

Package unit

30 tablets/bottle