Medication info

Citalopram 23 mg (Donepezil Hydrochloride Hydrate)

Prescription medicationTablet경구
Ingredient · strength
Donepezil Hydrochloride Hydrate›24mg / 1 tablet
Manufacturer / importer
에이치엘비제약(주)
Appearance
Red, bilaterally convex, round film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202102970 · Approved 2021.04.07

Summary

Main use
Treatment of moderate to severe Alzheimer's-type dementia symptoms
Who takes it
Adults
Adult dose
This medication should be taken once daily just before bedtime and can be administered regardless of meals. The initial recommended dose of Donepezil Hydrochloride is 5 mg once daily. Patients reach a stable condition after 15 days of administration, and 5 mg should be administered for 4 to 6 weeks. After clinical response evaluation, it can be increased to 10 mg. Care should be taken for adverse gastrointestinal reactions when increasing the dose to 10 mg daily. Maintain a minimum of 3 months on 10 mg.

Ingredients

Manufacturer
에이치엘비제약(주)

Efficacy & effects

Treatment of moderate to severe Alzheimer's-type dementia symptoms

  • Alzheimer's-type dementia symptoms
View approved original text

This medication is used to treat moderate to severe Alzheimer's-type dementia symptoms. It helps alleviate cognitive decline, cognitive dysfunction, and deterioration in the ability to perform daily activities, improving the quality of life. This treatment helps delay the progression of dementia symptoms and supports patients in living independently for as long as possible.

How to take

Adult dose

This medication should be taken once daily just before bedtime and can be administered regardless of meals. The initial recommended dose of Donepezil Hydrochloride is 5 mg once daily. Patients reach a stable condition after 15 days of administration, and 5 mg should be administered for 4 to 6 weeks. After clinical response evaluation, it can be increased to 10 mg. Care should be taken for adverse gastrointestinal reactions when increasing the dose to 10 mg daily. Maintain a minimum of 3 months on 10 mg.

Precautions

This medication should not be used in patients with allergies to specific ingredients or in pregnant or breastfeeding women. It should also not be administered to patients with hereditary lactose intolerance. Patients with heart disease or heart rhythm problems should be cautious while using this medication as it may cause irregular heart rhythms, necessitating regular ECG checks. Patients with a history of gastric ulcers or peptic ulcers should be cautious as symptoms may worsen with this medication. Patients with a history of asthma or obstructive pulmonary disease should also use this medication carefully as respiratory symptoms may worsen. Patients with extrapyramidal disorders such as Parkinson's disease need to be cautious as this medication may exacerbate their symptoms. This medication contains certain pigments, so patients with allergies to these should be aware. Various side effects such as nausea, vomiting, diarrhea, dizziness, fatigue, and loss of appetite may occur during treatment, so if symptoms are severe, you should consult a physician. Severe side effects may include heart problems, liver dysfunction, cerebrovascular anomalies, and muscle disorders, so report any unusual symptoms to medical personnel immediately. This medication is used in the treatment of Alzheimer's-type dementia, and the therapeutic effect should be regularly evaluated, and discontinuation should be considered if necessary. Caution is needed when driving or operating machinery as fatigue, dizziness, and muscle cramps may occur. This medication may interact with other medications, so you must inform healthcare professionals of any other drugs you are taking. Pregnant or breastfeeding women should avoid using this medication, and if necessary, should consult healthcare personnel before making a decision. Safety in pediatric patients has not been established, so it is not used in children. Overdose may result in severe nausea, vomiting, bradycardia, hypotension, respiratory depression, etc., and in such cases, immediate medical attention is required. Store this medication out of reach of children and do not transfer it to other containers.

Side effects and when to seek care immediately

Serious side effects

Syncope, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcer, perforated duodenal perforation, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, seizures, cerebral hemorrhage, cerebrovascular disorders, extrapyramidal disorders (motor dysfunction, ataxia, gait disturbances, etc.), neuroleptic malignant syndrome, rhabdomyolysis, respiratory distress, acute pancreatitis, acute renal failure, unexplained sudden death, cardiac arrest, severe allergic reactions (hives

Mild side effects

  • Nausea
  • vomiting
  • diarrhea
  • loss of appetite
  • headache
  • fatigue
  • lethargy
  • dizziness
  • insomnia
  • drowsiness
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  • itching
  • rash
  • myalgia
  • urinary incontinence
  • increased blood pressure
  • thrombocytopenia
  • anemia
  • dehydration
  • increased CPK
  • anxiety
  • hallucinations
  • aggressive behavior
  • drowsiness
  • psychomotor agitation
  • depression
  • confusion
  • dizziness
  • sweating
  • weight loss
  • hives
  • edema
  • bruising
  • fever
  • dry mouth
  • vasodilation
  • abnormal dreams
  • thrombocytopenia
  • hematological issues

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air or moisture entry. The storage temperature should be maintained between 1 and 30 degrees Celsius to preserve the effectiveness of the medication over time.

Appearance and packaging

Appearance

Red, bilaterally convex, round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.