Janudi Tablets 50mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered at a dose of 100 mg once daily for both monotherapy and combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dosage adjustments are required based on kidney function. No dosage adjustments are necessary for mild to moderate renal impairment (eGFR 45–90 mL/min/1.73 m2). In cases of moderate renal impairment (eGFR 30–45 mL/min/1.73 m2)

This medication may rarely cause severe allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur, consult a physician immediately. There is a risk of inflammation of the pancreas while taking this medication, so if sudden abdominal pain, vomiting, or nausea occurs, discontinue use immediately and go to the hospital. This medication is not used in patients with type 1 diabetes or diabetic ketoacidosis. Additionally, patients with hypersensitivity to this medication or its components should not take it. Patients with poor kidney function need dosage adjustments for this medication, so they should consult a physician regarding their kidney condition and undergo regular tests. Taking this medication with other hypoglycemic agents, especially insulin or sulfonylureas, can increase the risk of hypoglycemia, so blood sugar levels should be checked frequently, and dosage adjustments may be necessary. If severe pain in the neck or joints occurs while taking this medication, inform the physician, and if needed, the administration of medication can be discontinued. If blisters or severe rashes occur on the skin, immediately consult a physician and discontinue taking this medication. Women who are pregnant or nursing should avoid using this medication, and its safety and efficacy have not been confirmed for children or adolescents under 18 years of age. Elderly patients may have decreased kidney function, so kidney function tests should be performed before and after administration, and dosage adjustments may be necessary. In case of overdose, one should go to the hospital immediately for appropriate treatment, and this medication can be partially removed by hemodialysis. This medication has relatively few interactions with other drugs, but caution is needed when taken with cyclosporine or digoxin. It is important to regularly check one's health status according to the doctor's instructions while taking this medication.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, high fever with severe rash, blisters, skin peeling, oral/eye mucosal pain, severe skin adverse reactions, asthma attacks, respiratory issues accompanied by cough and fever, breathing problems, yellowing of skin or eyes (jaundice), liver problems, sudden and severe headache, lightning headache, seizures, confusion of consciousness

Mild side effects

• Nasopharyngitis
• upper respiratory infections
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• muscle pain
• limb pain
• back pain

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, at room temperature between 1 to 30 degrees Celsius. Storing it this way will safely maintain the effectiveness of the medication.

Appearance

Bright yellow-orange round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle