Janudy 25 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

The recommended dosage is 100 mg once daily for monotherapy or combination therapy, with a maximum daily dosage of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dosage adjustments may be necessary based on kidney function. - No dosage adjustment is needed for patients with mild to moderate renal impairment (eGFR 45–90 mL/min/1.73 m2). - For patients with moderate renal impairment (eGFR 30–45 mL/min/,

This medication may cause serious allergic reactions in some patients, so if you experience symptoms like skin rash, difficulty breathing, or swelling of the face or neck, immediately discontinue use and consult a doctor. Pancreatitis, an inflammation of the pancreas, may occur while taking this medication, so report any symptoms such as abdominal pain, nausea, or vomiting to healthcare providers promptly. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and should not be administered to individuals with allergies to this medication or its ingredients. Patients with impaired kidney function may need dosage adjustments due to slowed excretion of this medication, and regular kidney function tests should be performed. The risk of hypoglycemia may increase when this medication is used alone or in combination with other diabetes therapies, so be vigilant for hypoglycemia symptoms, and there may be a need to adjust the dosage of other medications if necessary. If severe joint pain or skin blistering symptoms occur, discontinue this medication and consult a doctor. Pregnant or breastfeeding women should avoid using this medication, and safety and efficacy have not been established in individuals under 18 years of age. Elderly patients may have impaired kidney function, making dosage adjustment and monitoring of kidney function important. In case of overdose, general emergency measures should be taken, and blood dialysis may be necessary to remove the medication. There are few significant drug interactions when combined with other medications, but caution is needed when taking specific drugs, so consult a doctor or pharmacist.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, Stevens-Johnson syndrome, exfoliative skin disease, severe skin adverse reactions, acute pancreatitis, pancreatitis, difficulty breathing, respiratory issues, liver abnormalities (elevated liver enzymes, symptoms suggestive of jaundice), severe and debilitating joint pain, blistering dermatitis, blood abnormalities (including thrombocytopenia), acute kidney failure, severe allergic reactions, rash, hives, severe hypoglycemia,

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• constipation
• vomiting
• diarrhea
• muscle pain
• limb pain
• back pain
• pruritus

Store this medication in a tightly sealed container to prevent air from entering, and it is recommended to keep it at room temperature between 1 degree and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness.

Appearance

Bright yellow-orange round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle