Janudy 100 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered as monotherapy or in combination therapy at a dose of 100 mg once daily, with a maximum daily dose of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dosage adjustments may be required based on kidney function. - In patients with mild renal impairment (eGFR 60 to 90), dosage adjustment is not necessary. - In patients with moderate renal impairment (eGFR 45 to 60), dosage adjustment is necessary.

This medication may cause serious allergic reactions in some patients; if symptoms such as skin rash or difficulty breathing occur after administration, discontinue use immediately and consult a physician. This medication may cause pancreatitis, a condition in which inflammation occurs in the pancreas; therefore, if symptoms such as abdominal pain, nausea, or vomiting occur during use, visit a healthcare facility immediately. Patients with type 1 diabetes or diabetic ketoacidosis should not use this medication. Patients who have had allergic reactions to this medication or its components should not use it. Patients with impaired kidney function may need dosage adjustments, and it is important to undergo regular kidney function tests. This medication carries a risk of hypoglycemia, especially when used in conjunction with insulin or sulfonylureas, so symptoms of hypoglycemia should be closely monitored. Some patients may experience side effects such as headache, upper respiratory infection, nasopharyngitis, diarrhea. If symptoms such as severe joint pain or skin blistering occur, inform a doctor immediately and discontinue use of the medication. Women who are pregnant or breastfeeding are advised not to take this medication. This medication generally has fewer interactions when combined with other drugs; however, it is best to consult a physician or pharmacist when taking it with specific drugs. In the case of overdose, immediate medical attention should be sought, and some may be removed via dialysis. Elderly patients may have decreased kidney function, necessitating dosage adjustments and monitoring.

Serious side effects

Urticaria, angioedema, anaphylaxis, Stevens-Johnson syndrome, exfoliative skin disease, acute pancreatitis, acute renal failure, severe rash, blisters, skin peeling, oral/ocular mucosal pain, difficulty breathing, asthma attacks, shortness of breath, jaundice, elevated liver enzymes, sudden and severe headache, seizures, confusion, vision disturbances, paralysis, severe swelling, urinary abnormalities, severe joint pain accompanied by disability, blistering dermatitis

Mild side effects

• Nasopharyngitis
• upper respiratory infection
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• myalgia
• limb pain

Store this medication in a sealed container to prevent exposure to air and moisture, and it is best to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will maintain the medication's efficacy and prevent deterioration.

Appearance

Bright yellow-orange round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle