Widerpe Tablet 23 mg (Donepezil Hydrochloride Hydrate)

Adult dose

This medication is taken once daily just before bedtime, and can be administered without regard to meals. The initial recommended dose of Donepezil Hydrochloride is 5 mg taken once daily. Normal status is reached 15 days after administration, and for 4-6 weeks, 5 mg should be given. After evaluating clinical response, the dose can be increased to 10 mg. When increasing to 10 mg daily, caution is required for gastrointestinal adverse reactions. At least 3 months on 10 mg is required.

This medication contains Donepezil Hydrochloride Hydrate as its active ingredient, primarily used to alleviate symptoms of Alzheimer's disease. First, if there is a hypersensitivity to this medication or an allergy to its components, if the patient is pregnant or breastfeeding, or if there is a genetic issue such as lactose intolerance, this drug should not be taken. Patients with heart disease or heart conduction disorders should be cautious as this medication may affect cardiac rhythm. Patients taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should use this medication with caution as it may put stress on the stomach. Asthma or chronic obstructive pulmonary disease patients should be aware that this medication may cause bronchoconstriction. Patients with extrapyramidal disorders such as Parkinson's disease should also be careful as symptoms may worsen with this medication. This drug contains Yellow No. 5 (Tartrazine) which may cause allergic reactions in sensitive individuals. Side effects during use may include dizziness, nausea, vomiting, diarrhea, loss of appetite, etc., and in severe cases, serious side effects such as heart issues or liver dysfunction, seizures may occur; consult a healthcare professional immediately if any abnormal symptoms arise. This drug may affect liver and kidney function, thus regular testing and monitoring are required. Additionally, this medication has many interactions with other drugs, so particularly if taking heart medications, antibiotics, antidepressants, or anticonvulsants, consult your doctor. Women who are pregnant or breastfeeding should avoid using this drug, and if it is essential, it should be decided with caution under professional supervision. For children's safety, this medication is not recommended for use in pediatric patients. In cases of overdose, serious symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur, so it is essential to adhere to the dosage, and in cases of overdose, visit the hospital immediately. When storing, keep out of reach of children and do not transfer to other containers. Finally, this drug should be taken following a doctor's diagnosis and prescription to improve Alzheimer's symptoms, and it is important to regularly evaluate treatment efficacy and side effects.

Serious side effects

Fainting, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, gastrointestinal bleeding, peptic ulcer, perforated duodenal perforation, hepatitis, liver dysfunction, jaundice, cerebral seizures (epilepsy, convulsions), cerebral hemorrhage, cerebrovascular disorders, extrapyramidal disorders (motor dysfunction, ataxia, tremors, etc.), neuroleptic malignant syndrome (stupor, muscle rigidity, swallowing difficulty, tachycardia, sweating, fever), rhabdomyolysis, respiratory distress, acute

Mild side effects

Nausea, vomiting, diarrhea, loss of appetite, headache, fatigue, lethargy, dizziness, insomnia, drowsiness, fever, swelling, changes in blood pressure (hypertension, hypotension), palpitations, sweating, itching, rash, hallucinations, agitation, aggressive behavior, nightmares, mental disturbances, drowsiness, hematologic disorders (anemia, leukopenia, thrombocytopenia, etc.), myalgia, muscle cramps, urinary incontinence, increased urination, urination disorders, weight loss, bruise, abdominal pain, cramps

This medication should be stored in a tightly sealed container to prevent air from entering and kept at a temperature between 1 to 30 degrees Celsius. Storing it this way can help maintain the drug's effectiveness for a long time.

Appearance

Red, biconvex, round film-coated tablet

Package unit

30 tablets/bottle