Unipezil Tablet 23 mg (Donepezil Hydrochloride Hydrate)

Adult dose

This medication is taken once daily just before bedtime, and can be administered regardless of food intake. The initial recommended dosage of Donepezil Hydrochloride is 5 mg taken once daily. After administering 5 mg for 4 to 6 weeks, clinical response should be evaluated to increase the dosage up to 10 mg. When increasing the dosage to 10 mg per day, caution should be exercised for gastrointestinal adverse reactions. It should be taken at least for 3 months at a dosage of 10 mg once daily.

This medication contains Donepezil Hydrochloride as its main ingredient and is used for the treatment of Alzheimer-type dementia. Firstly, this medication should not be used by individuals who are allergic to Donepezil Hydrochloride or any of its components, pregnant women or women who may become pregnant, and those with lactose intolerance or genetic lactose metabolism disorders. Patients with heart diseases or heart conduction disorders should use this medication cautiously, as bradycardia or arrhythmias may occur during use. Those taking non-steroidal anti-inflammatory drugs (NSAIDs) or with a history of peptic ulcers should be careful, as this medication can promote gastric acid secretion and worsen symptoms. Patients with asthma or obstructive pulmonary diseases should be cautious, as bronchoconstriction and increased mucus secretion may exacerbate their symptoms. Patients with extrapyramidal disorders such as Parkinson's disease may have worsening symptoms due to the cholinergic effects of this medication. This medication contains Yellow No. 4 dye, so individuals allergic to this component should exercise caution. During treatment, serious side effects such as syncope, bradycardia, heart block, gastrointestinal bleeding, liver dysfunction, cerebrovascular issues, movement disorders, severe muscle symptoms, difficulty breathing, acute pancreatitis, and renal failure may occur. If any abnormal symptoms arise, consult a physician immediately. Additionally, relatively common side effects such as nausea, vomiting, diarrhea, loss of appetite, dizziness, insomnia, headache, fatigue, and others may also occur. This medication should be used under the supervision of a physician experienced in the diagnosis and treatment of dementia symptoms, and treatment efficacy should be evaluated regularly. Patients with heart diseases, electrolyte imbalances, or a history of prolonged QT intervals may require heart monitoring during use. Caution should be exercised when driving or operating machinery, as dizziness, fatigue, and muscle cramps may occur. Pregnant or breastfeeding women should avoid using this medication, and if necessary, should consult with a specialist. This medication may interact with other drugs, so it is essential to inform your doctor or pharmacist, especially if you are taking medications related to CYP3A4 and CYP2D6, heart medications, anticholinergic medications, NSAIDs, etc. In cases of overdose, serious symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur, and immediate medical attention should be sought. Lastly, this medication should be stored out of reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, abnormal breathing accompanied by cough and fever, skin or eyes turning yellow (jaundice), extreme fatigue throughout the body, sudden and severe headache, lightning headache, seizures, confusion of consciousness, visual disturbances, paralysis, reduced urine output

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• lethargy
• dizziness
• drowsiness
• insomnia

This medication should be stored in a tightly closed container to prevent air or moisture exposure. It is advisable to store it at room temperature, between 1 and 30 degrees Celsius.

Appearance

Red, biconvex, round film-coated tablet

Package unit

30 tablets/bottle