Glucitagl Tablet 100 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

For monotherapy or combination therapy, the dose is 100 mg once daily, with a maximum daily dose of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dose adjustments are required based on kidney function. - In patients with mild renal impairment (eGFR 60 to < 90), no dosage adjustment is needed. - In patients with moderate renal impairment (eGFR 45 to < 60), no dosage adjustment is needed.

This medication can cause severe allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck appear after taking it, you should immediately stop taking it and consult a doctor. There is a risk of developing serious inflammation of the pancreas (pancreatitis) while taking this medication, so if sudden abdominal pain, vomiting, or nausea occur, you should promptly inform healthcare professionals. Patients with type 1 diabetes or diabetic ketoacidosis should not take this medication, and patients who have experienced an allergic reaction to this medication or its components should also avoid it. Patients with impaired renal function may require dosage adjustments, so if you have kidney disease or reduced kidney function, you should consult a doctor before taking it. Side effects such as upper respiratory tract infections, nasopharyngitis, headache, diarrhea, nausea may occur during treatment. If symptoms are severe or persist for a long time, you should inform your doctor. The risk of hypoglycemia may increase when taking this medication with other antidiabetic agents, particularly insulin or sulfonylureas, hence blood glucose levels should be regularly monitored, and if necessary, dosage adjustments should be made. This medication can cause rare side effects, such as severe joint pain or the skin disease bullous pemphigoid. If severe joint pain or skin blisters or rashes develop, immediate medical attention is necessary. The safety of this medication during pregnancy or breastfeeding has not been established, so it's not recommended to take it. Its efficacy and safety in children under 18 years have not been adequately confirmed. Elderly patients may have impaired renal function, making it important to adjust the dosage and regularly monitor kidney function. In cases of overdose, you should immediately visit a medical institution for appropriate treatment. This medication can be partially removed by hemodialysis, so dialysis treatment may be considered if necessary.

Serious side effects

Urticaria, severe swelling (angioedema), anaphylaxis, severe allergic reactions, severe rash, bullous pemphigoid, Stevens-Johnson syndrome, exfoliative skin disease, mouth/eye mucosal pain, acute pancreatitis, liver abnormalities (including elevated liver enzymes), acute renal failure, severe and disabling arthralgia, rhabdomyolysis, severe pancreatitis, severe hypoglycemia, severe edema accompanied by elevated blood pressure, pneumonia, cardiac arrest, critical condition

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• constipation
• vomiting
• headache
• myalgia
• limb pain
• back pain
• pruritus
• thrombocytopenia

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, and it is recommended to keep it at a temperature between 1 and 30 degrees Celsius. Proper storage helps to maintain the effectiveness of the medication.

Appearance

Bright yellow-orange round film-coated tablets

Package unit

100 tablets/bottle, 30 tablets/bottle