Glipizide Tablet 25 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

This drug is administered once daily at a dose of 100 mg in monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dosage adjustments are required based on renal function. - Mild renal impairment (eGFR 60 or above and less than 90): No dosage adjustment needed - Moderate renal impairment (eGFR 45 or above and less than 60): No dosage adjustment needed - Moderate renal impairment (

This drug can rarely cause serious allergic reactions, so if symptoms such as rash or difficulty breathing occur, it should be discontinued immediately, and a doctor should be consulted. Acute pancreatitis may occur during the use of this drug, so if abdominal pain, vomiting, or severe abdominal pain occurs, medical personnel should be notified immediately. This drug should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and patients who are allergic to this drug or its components should also avoid its use. Patients with renal impairment need to adjust the dosage of this drug and should undergo regular renal function tests. Hypoglycemic symptoms may occur when this drug is used alone or in combination with other antidiabetic medications, so caution should be exercised when taken with medications that pose a risk of hypoglycemia, and adjustments to the dosages of other medications may be necessary. Symptoms such as headache, upper respiratory tract infection, nasopharyngitis, diarrhea may occur during the use of this drug, and if these symptoms persist or worsen, it is advisable to consult a doctor. If severe joint pain or blistering skin symptoms occur, the use of this drug should be discontinued immediately, and medical personnel should be consulted. It is recommended that women who are pregnant or breastfeeding do not take this drug, and the safety and efficacy in children under 18 have not been established. Elderly patients may require dosage adjustment and monitoring of renal function due to the potential for renal impairment. In cases of overdose, general emergency treatment can be applied and some medications can be removed through hemodialysis, so if overdose is suspected, medical institutions should be visited immediately.

Serious side effects

Urticaria, angioedema, anaphylaxis, Stevens-Johnson syndrome and other exfoliative skin diseases, severe allergic reactions, acute pancreatitis, acute renal failure, severe and debilitating joint pain, blistering similar to pemphigus, rhabdomyolysis, pneumonia, cardiac arrest, diabetic complications, metabolic acidosis, severe skin adverse reactions

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• diarrhea
• nausea
• constipation
• indigestion
• dizziness
• muscle pain
• limb pain

This drug should be stored in a tightly closed container to prevent air and moisture from entering. It is advisable to maintain a storage temperature between 1 to 30 degrees Celsius to ensure the drug's efficacy and safety.

Appearance

Bright yellow-orange round film-coated tablets

Package unit

100 tablets/bottle, 30 tablets/bottle