Pharma Empaglow 25 mg (Empagliflozin)

Adult dose

The recommended dose for this medication as monotherapy or as an adjunct with other blood glucose-lowering agents, such as insulin, is 10 mg once daily. If additional blood sugar control is needed and the patient tolerates it well, the dose may be increased to 25 mg once daily. When co-administering with sulfonylureas or insulin, consider reducing the dose of sulfonylureas or insulin to decrease the risk of hypoglycemia. It can be taken without regard to meals.

This medication should not be given to certain patients. First, patients with allergic reactions to this medication's active ingredient or any of its components should not take it. Secondly, it is not to be used in patients with type 1 diabetes or diabetic ketoacidosis. Thirdly, patients with severely impaired kidney function, specifically those with a glomerular filtration rate of less than 30 mL/min/1.73m2, or those with end-stage renal disease or on dialysis should not take this medication. Fourthly, patients with genetic issues such as lactose intolerance or galactose intolerance should also avoid this medication. This medication should be used with caution in patients with mild kidney impairment. For those with a glomerular filtration rate of less than 60 mL/min/1.73m2, treatment initiation should be avoided, and if already on the medication, dosage adjustment or discontinuation may be necessary. It is not effective and not to be used in patients with end-stage renal disease or who are on dialysis. In patients with heart failure, especially mild to moderate cases, it should be used cautiously, and it is not recommended for those with severe heart failure. When combined with insulin or sulfonylureas, which stimulate insulin secretion, there is a risk of hypoglycemia, so dosage adjustments of these medications may be necessary. This medication may cause side effects including hypoglycemia, genital infections, increased urination, urinary tract infections, and decreased fluid volume. If any unusual symptoms appear, patients should consult a healthcare professional immediately. Especially, serious metabolic acidosis known as ketoacidosis may occur, so if symptoms such as nausea, vomiting, abdominal pain, or respiratory distress occur, patients should visit a hospital immediately. Elderly patients or those at risk of fluid loss should be cautious about dehydration and hypotension, and the administration of this medication may be temporarily suspended if necessary. This medication may affect kidney function, so regular kidney function tests are important. Additionally, it is advisable to avoid the use of this medication during pregnancy and to cease breastfeeding if currently nursing. Safety and efficacy have not been established for children and adolescents under 18, so it should not be used in these populations. No specific toxic reactions have been reported in cases of overdose, but appropriate treatment may be required based on clinical conditions. This medication may interact with other drugs, so patients taking other medications should inform their healthcare provider, especially when taking diuretics, insulin, or sulfonylureas. Finally, this medication should be kept out of reach of children, and it is safer not to transfer it to another container.

Serious side effects

Hives, severe swelling (edema), angioedema, ketoacidosis, urosepsis, pyelonephritis, necrotizing fasciitis, liver damage (including signs of liver dysfunction), sudden and severe headache, intracranial aneurysm, seizures, confusion, vision changes, paralysis, significant decrease in urine output, generalized edema, hypertension, deep vein thrombosis, angina, unstable angina, stent thrombosis, acute kidney injury, acute cholecystitis.

Mild side effects

• Hypoglycemia
• vulvovaginal candidiasis
• balanitis
• other genital infections
• increased urination
• urinary tract infections
• decreased fluid volume
• increased blood creatinine
• decreased glomerular filtration rate
• rash

This medication should be stored in a closed container to protect it from air and moisture. The appropriate storage temperature is room temperature between 1°C and 30°C. Avoid storing in excessively hot or cold places.

Appearance

Light yellow, biconvex, oval film-coated tablet

Package unit

30 tablets/bottle