AlcloXib Tablet 30 mg (Etoricoxib)

Adult dose

Before administering this medicine, consider the potential risks and benefits of this medicine and other alternative treatments. As cardiovascular risk increases with increasing dose and duration of exposure, administer for the shortest possible duration. Because adverse reactions such as hypertension, congestive heart failure, and edema may occur during treatment, periodically, at least monthly, reassess whether treatment should be continued based on the patient's symptom relief and response to treatment. This medicine may be administered with or without food. Adults: The recommended dose is 30 mg once daily; do not exceed 30mg per day. If there is no therapeutic benefit at the recommended dose, discontinue this medicine and consider an appropriate alternative treatment. Patients with hepatic impairment: No dosage adjustment is required in patients with mild or moderate hepatic impairment (Child-Pugh score 5-9). However, caution should be exercised when administering this medicine to patients with moderate hepatic impairment because experience is limited. Do not administer this medicine to patients with severe hepatic impairment (Child-Pugh score >9), as there is no experience in these patients. Patients with renal impairment: No dosage adjustment is required in patients with mild or moderate renal impairment (creatinine clearance of 30 mL/min or greater). Do not administer this medicine to patients with severe renal impairment (creatinine clearance below 30 mL/min). Elderly patients: No dosage adjustment is required in elderly patients.

This medication may cause serious side effects such as gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic beverages daily, so it is essential to consult a doctor or pharmacist. Additionally, this medication may increase the risk of cardiovascular diseases such as heart attack or stroke, so individuals with cardiovascular diseases or risk factors should exercise caution and use the lowest effective dose for the shortest duration possible. Serious gastrointestinal problems such as gastrointestinal bleeding, ulcers, or perforation may occur; therefore, caution should be exercised in individuals with gastrointestinal conditions or older adults. This medication may trigger certain allergic reactions; thus, do not take it if you are allergic to this medication or similar drugs. Patients with uncontrolled hypertension, severe heart failure, markedly reduced liver or kidney function, active peptic ulcer, inflammatory bowel disease, or those who are pregnant or breastfeeding should not use this medication. Patients with diminished liver or kidney function, asthma, hypertension, diabetes, history of heart failure, or edema need to exercise caution when taking this medication and should do so under a doctor's guidance. While taking this medication, regular monitoring of blood pressure, liver function, kidney function, and blood tests is recommended to detect and address any anomalies early. This medication can cause various side effects, including common symptoms like dyspepsia, headache, dizziness, edema, and hypertension. In severe cases, skin rash, breathing difficulties, and heart irregularities may occur, so contact medical personnel immediately if unusual symptoms arise. Moreover, this medication can interact with other drugs, so inform your doctor, especially if you are taking anticoagulants, antihypertensive medications, diuretics, immunosuppressants, or oral contraceptives. Women who are pregnant or planning to become pregnant should avoid this medication, as it may be harmful to the fetus; breastfeeding mothers should also avoid using this medication or stop breastfeeding. The safety and efficacy of this medication have not been established in children under 18 years of age; therefore, it is advisable not to use it. Elderly patients are more likely to have decreased kidney, liver, and heart function; thus, careful monitoring and management are particularly necessary when using this medication. In case of overdose, symptoms may include nausea, vomiting, drowsiness, and lethargy, and in severe cases, gastrointestinal bleeding or kidney failure may occur, so seek medical attention immediately. Finally, store this medication out of reach of children, and do not transfer it to another container. Avoid driving or operating machinery if dizziness or drowsiness occurs during use.

Gastrointestinal bleeding, serious cardiovascular thrombotic reactions, myocardial infarction, stroke, bleeding from the stomach or intestines, ulcer, perforation, osteomyelitis, gastritis, upper respiratory infection, urinary tract infection, anemia, leukopenia, thrombocytopenia, hypersensitivity reactions, angioedema, anaphylaxis, shock, edema, fluid retention, increased appetite, decreased appetite, weight gain, anxiety, depression, reduced mental capacity, hallucinations, confusion, restlessness, dizziness, headache, taste disturbances, insomnia, sensory disturbances, sensory loss, drowsiness, intracranial bleeding, blurred vision, conjunctivitis, tinnitus, vertigo, palpitations, arrhythmia, atrial fibrillation, tachycardia, congestive heart failure, nonspecific ECG changes, angina pectoris, myocardial infarction, hypertension, flushing, cerebrovascular events, transient ischemic attacks, hypertensive crises, vasculitis, deep vein thrombosis, bronchospasm, cough, dyspnea, nosebleeds, pulmonary embolism, abdominal pain, constipation, bloating, gastritis, heartburn, acid reflux, diarrhea, dyspepsia, upper abdominal discomfort, nausea, vomiting, esophagitis, oral ulcers, abdominal distension, changes in bowel movement, dry mouth, gastric duodenal ulcers, gastrointestinal perforation, peptic ulcer, irritable bowel syndrome, pancreatitis, increased alanine aminotransferase, increased aspartate aminotransferase, hepatitis, liver failure, jaundice, petechiae, facial edema, pruritus, rash, erythema, urticaria, Stevens-Johnson syndrome, toxic epidermal necrolysis, fixed drug eruption, muscle cramps, musculoskeletal pain, musculoskeletal stiffness, proteinuria, increased serum creatinine, renal failure, renal impairment, weakness, fatigue, flu-like illness, chest pain, increased blood urea nitrogen, increased creatine phosphokinase, hyperkalemia, increased uric acid, decreased serum sodium, facial swelling, chest discomfort, tremors, visual impairment, insomnia, sensory disturbances, abnormal dreams

Store this medication in a tightly sealed container as it is susceptible to air and moisture. It is best to maintain storage temperatures between 1 and 30 degrees Celsius.

Appearance

Greenish-blue, apple-shaped, convex film-coated tablet

Package unit

For domestic use - 30 tablets/box [(10 tablets/Alu-Alu * 3)]