Sitagliptin 25 mg Tablet (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg in monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dosage adjustment is necessary based on renal function. 1. No dosage adjustment is needed for mild renal impairment (eGFR 60 to 90). 2. No dosage adjustment is needed for moderate renal impairment (eGFR 45 to 60).

This medication is an agent used for diabetes treatment and helps in blood sugar management. However, serious allergic reactions may occur during treatment, so if symptoms such as skin rash or difficulty breathing develop, it is essential to stop taking this medication immediately and consult a doctor. Moreover, there is a risk of pancreatitis, which is inflammation of the pancreas, so if abdominal pain, vomiting, or severe abdominal pain occurs, notify medical personnel immediately. Patients with Type 1 diabetes or certain allergies should not take this medication. Patients with impaired kidney function should have their dosage adjusted, and consultation with a doctor regarding renal status is necessary. Mild adverse reactions such as cold symptoms, headache, or rhinitis may occur during treatment. When taken with other glucose-lowering agents or insulin, the risk of hypoglycemia may increase, so attention should be paid to symptoms of hypoglycemia, and dosage adjustments may be necessary. Pregnant or nursing women should refrain from using this medication, and safety in children or adolescents under 18 has not been thoroughly confirmed. Elderly individuals may have a risk of declining kidney function, so renal function tests before and after use are recommended. In the event of an overdose, seek medical attention immediately for appropriate treatment, and this medication may be partially removed by dialysis. If any unusual symptoms appear while taking this medication, please consult medical personnel for appropriate action.

Serious side effects

Urticaria, severe swelling (angioedema), severe allergic reactions (anaphylaxis), severe skin reactions (Stevens-Johnson syndrome, rashes, exfoliative skin disease), acute pancreatitis (hemorrhagic or necrotizing pancreatitis), difficulty breathing, severe joint pain accompanied by morbidity and disability, bullous pemphigoid, liver abnormalities (including elevated liver enzymes and possible jaundice), acute renal failure, cardiac arrest, severe hypoglycemia, pneumonia, diabetes complications, metabolic disorders

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• nausea
• constipation
• myalgia
• limb pain
• back pain
• pruritus

This medication should be stored in a sealed container to avoid exposure to air and kept at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance

Round film-coated tablet, bright yellow-orange

Package unit

30 tablets/bottle, 100 tablets/bottle