Sitagliptin 50 mg (Sitagliptin Hydrochloride Monohydrate) Tablet

Adult dose

This medication is administered once a day at a dose of 100 mg for monotherapy or combination therapy, with a maximum allowable dose of 100 mg per day. It can be taken regardless of meals. In patients with renal impairment: - For mild to moderate renal impairment (eGFR ≥ 45 mL/min/1.73 m2), no dosage adjustment is necessary. - For moderate renal impairment (eGFR ≥ 30 and < 45 mL/min/1.73 m2), the dosage is 1

This medication may cause serious allergic reactions after administration, so if symptoms such as rash or difficulty breathing occur, discontinue use immediately and consult a physician. There is also a risk of serious inflammation of the pancreas known as pancreatitis, so if symptoms like abdominal pain or vomiting arise, inform medical personnel promptly. This medication should not be used by patients with type 1 diabetes or diabetic ketoacidosis, nor in cases of hypersensitivity to this medication or its components. Patients with decreased renal function should have their dosage adjusted, hence regular renal function tests are necessary. During the course of this medication, hypoglycemic symptoms may occur, especially when taken with insulin or sulfonylureas, so blood sugar levels should be closely monitored. If severe joint pain or blisters on the skin occurs, notify a doctor immediately and discontinue the medication. Pregnant or nursing women are advised to avoid using this medication, and safety in children and adolescents under 18 years has not been established. Elderly individuals may have decreased renal function, so dosage adjustment and renal function testing is required. Be aware that interactions may occur when taken with other medications, so inform healthcare providers of any concurrent medications being taken. In the case of overdose, visit a hospital immediately for appropriate treatment, and this medication can be partially removed by dialysis.

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing, anaphylaxis, severe hypersensitivity reactions, Stevens-Johnson syndrome (severe skin reactions), acute pancreatitis (life-threatening/non-life threatening hemorrhagic or necrotizing), dyspnea or difficulty breathing, asthma attack, yellowing of skin or eyes (jaundice), sudden and severe headache, seizures, consciousness disturbance, visual disturbances, paralysis, markedly reduced urine output

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• abdominal pain
• nausea
• constipation
• myalgia
• limb pain
• back pain

This medication should be stored in a tightly closed container to prevent air or moisture exposure and kept at room temperature between 1 and 30 degrees Celsius. Proper storage will maintain the medication's effectiveness and ensure safe use.

Appearance

Bright yellow-orange round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle