Sita Down Tablets 25 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

For monotherapy or combination therapy, this medication is administered at a dosage of 100 mg once daily, with a maximum daily dose of 100 mg. It can be taken without regard to meals. Dosage adjustments may be required based on kidney function. - Mild renal impairment (eGFR ≥ 60 and < 90 mL/min/1.73 m²): No dosage adjustment necessary - Moderate renal impairment (eGFR ≥ 45 and < 60 mL/

This medication may cause severe allergic reactions after administration; therefore, if symptoms like skin rash or difficulty breathing occur, use should be discontinued immediately, and a physician should be consulted. This medication has the potential to cause a serious pancreatic disease called pancreatitis, so if symptoms like abdominal pain or vomiting occur, healthcare personnel should be notified immediately. Patients with type 1 diabetes or diabetic ketoacidosis should not use this medication, and those allergic to this drug or its ingredients should also avoid administration. Patients with impaired kidney function may have delayed excretion of this medication, so dosage adjustments or careful use may be necessary. While using this medication, symptoms such as headaches, cold symptoms, rhinitis, indigestion, and diarrhea may occur; if symptoms persist, it is advised to consult a physician. When taken together with insulin or sulfonylureas, the risk of hypoglycemia may increase; therefore, blood sugar levels should be checked regularly, and dosage adjustments may be needed if necessary. Severe joint pain or bullous pemphigoid may occur, so if these symptoms appear, medication should be discontinued immediately, and a specialist's care should be sought. Pregnant or breastfeeding women are advised to avoid the use of this medication, and its safety has not been established in children and adolescents under 18 years of age. For the elderly, it is important to adjust the dosage and periodically monitor kidney function since kidney function may decline. In cases of overdose, general emergency measures should be taken, and hemodialysis may be performed if necessary to remove the drug. This medication has confirmed cardiovascular safety and does not increase the risk of heart disease, but regular check-ups are recommended during administration. While the potential for drug interactions is low, it is advisable to inform healthcare personnel of any medications being taken and to receive appropriate monitoring.

Serious side effects

• Urticaria
• severe swelling (angioedema)
• anaphylaxis
• Stevens-Johnson syndrome
• severe skin reactions
• acute pancreatitis
• acute renal failure
• severe and disabling joint pain
• bullous pemphigoid
• rhabdomyolysis

Mild side effects

• Hypoglycemia
• upper respiratory infection
• nasopharyngitis
• headache
• constipation
• vomiting
• muscle pain
• limb pain
• back pain
• pruritus

This medication should be stored in a tightly sealed container to prevent exposure to air or humidity, and it is best to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage can help maintain the drug's efficacy over time.

Appearance

Bright yellow-orange round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle