Huglyia Tablet 50 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg, whether as monotherapy or combination therapy, with a maximum daily dose of 100 mg. In cases of moderate renal impairment (glomerular filtration rate [eGFR] 30-45 mL/min/1.73 m2), a dose of 50 mg once daily is indicated. For severe renal impairment (glomerular filtration rate [eGFR] 15-30 mL/min/1.73 m2) or patients requiring hemodialysis or peritoneal dialysis, the dosage should be adjusted according to kidney function.

This medication may cause allergic reactions; therefore, if symptoms such as skin rash or difficulty breathing occur after administration, discontinue use immediately and consult a doctor. While taking this medication, symptoms of pancreatitis, such as severe abdominal pain, vomiting, and fever may occur, so if these symptoms appear, immediately discontinue the medication and visit a hospital. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and it should not be administered to those with allergies to this medication or its components. Patients with decreased kidney function need to adjust the dosage of this medication, so appropriate dosing must be determined through kidney function tests. When using this medication with other blood sugar-lowering agents, particularly insulin or sulfonylureas, the risk of hypoglycemia may increase; thus, careful monitoring of blood sugar levels is required, and dosage adjustments should be considered as needed. In some patients, severe joint pain or skin conditions may occur; if such symptoms arise, consult a physician immediately to determine whether to discontinue the medication. Pregnant or breastfeeding women are advised not to use this medication, and safety in pediatric patients has not been sufficiently established. Elderly patients are more likely to have impaired kidney function, so kidney function should be monitored regularly, and dosage adjustments made when administering this medication. In case of overdose, general treatment such as removing the medication from the gastrointestinal tract should be performed, and if necessary, hemodialysis may be carried out to remove the drug. This medication has minimal interactions with other drugs, but it is advisable to consult a physician or pharmacist when taking certain medications.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, rash, exfoliative skin diseases (including Stevens-Johnson syndrome), severe and debilitating joint pain, bullous pemphigoid, acute pancreatitis, acute renal failure, elevated liver enzymes, liver abnormalities (including jaundice), severe hypoglycemia, pneumonia, cardiac arrest, acute renal failure, worsening of kidney function

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• constipation
• vomiting
• headache
• muscle pain
• limb pain
• back pain
• pruritus
• thrombocytopenia

This medication should be stored in a tightly sealed container to prevent air exposure, preferably at room temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the medication's effectiveness and prevent degradation.

Appearance

Bright yellow-orange round film-coated tablets

Package unit

100 tablets/bottle, 30 tablets/bottle