Glycita Tablets 100 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This drug is administered once daily at a dose of 100 mg, whether used alone or in combination, with a maximum daily dose of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dose adjustment is required based on renal function. - For mild renal impairment (eGFR 60–90 mL/min/1.73 m2): No dose adjustment necessary - For moderate renal impairment (eGFR 45–60 mL/min/1.73 m2): Dose adjustment

This drug may cause severe hypersensitivity reactions; thus, if an allergic reaction is suspected, use should be immediately discontinued and medical consultation should be sought. Acute pancreatitis may occur; thus, if symptoms such as abdominal pain, nausea, or vomiting appear, prompt medical attention is necessary. It is not safe to use this drug in patients with type 1 diabetes or diabetic ketoacidosis. Patients with impaired renal function should have their dosing adjusted, and regular renal function testing is important. Hypoglycemic symptoms may occur during treatment; therefore, monitoring blood glucose carefully is necessary, especially when taken in conjunction with insulin or sulfonylureas. If severe joint pain or skin blisters arise, discontinue use of this drug immediately and inform a healthcare professional. Pregnant or breastfeeding women should avoid using this drug, and its safety in children or adolescents under 18 years has not been established. Elderly patients may experience decreased renal function, so dose adjustments and regular renal function testing are required. In cases of overdose, symptomatic treatment, including the removal of the drug from the gastrointestinal tract, may be necessary, and some may be removed by dialysis. Drug interactions are minimal; however, caution is required when used with digoxin or cyclosporine. This drug is proven to have cardiovascular safety, but if any unusual symptoms arise during administration, immediate consultation with a healthcare professional is advised.

Serious side effects

• Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor → severe allergic reaction
• Severe rash with high fever, blisters, skin peeling, mucosal pain in mouth/eyes → severe skin adverse reaction
• Shortness of breath or difficulty breathing, asthma attacks, cough accompanied by fever and respiratory issues → respiratory problems
• Skin or eyes turning yellow (jaundice), extreme lethargy → liver abnormalities (jaundice)
• Sudden

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• constipation
• vomiting
• myalgia
• limb pain
• back pain
• pruritus
• thrombocytopenia

This drug should be stored in a tightly sealed container to prevent air exposure and is best kept at room temperature between 1 to 30 degrees Celsius. Storing it this way will help maintain its effectiveness.

Appearance

Bright brown, round, biconvex film-coated tablets

Package unit

28 tablets/box [14 tablets/PTPX2]