Glycita Tablet 50 mg (Sitagliptin Hydrochloride Hydrate)

Adult dosage

This medication is administered once daily at a dose of 100 mg, either as monotherapy or in combination therapy, with a maximum daily dose of 100 mg. It can be taken without regard to meals. For patients with renal impairment, dose adjustment is necessary according to kidney function. 1. For mild renal impairment (eGFR 60-90 mL/min/1.73 m2), no dose adjustment is necessary. 2. For moderate renal impairment (eGFR 45-60 mL/min/1.73 m2), dose adjustment is not required.

This medication may cause severe hypersensitivity reactions after administration, so if allergy symptoms are suspected, use should be discontinued immediately. Symptoms of serious pancreatic issues such as acute pancreatitis may appear, so caution is advised for symptoms such as abdominal pain or vomiting. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor should it be administered to patients allergic to this medication or any of its ingredients. Dose adjustment is necessary for patients with reduced kidney function, so regular kidney function tests should be conducted. Reported side effects in clinical trials include upper respiratory infections, headaches, nasopharyngitis, dyspepsia, diarrhea, and hypoglycemic symptoms may also occur. When taken with other blood sugar lowering agents, especially insulin or sulfonylureas, there is an increased risk of hypoglycemia, so caution is required. Severe adverse reactions such as serious joint pain or skin blisters may occur, and if these symptoms appear, immediate consultation with healthcare professionals is necessary. It is preferable for women who are pregnant or breastfeeding not to take this medication, and the safety of this medication for children and adolescents under 18 years of age has not been established. In the case of overdose, general treatment should be administered, and if necessary, hemodialysis can be performed to remove the drug. This medication does not pose safety concerns regarding cardiovascular effects, and it can be used relatively safely in elderly individuals, although kidney function status should be monitored regularly.

Serious side effects

Urticaria, severe hypersensitivity reaction (anaphylaxis, angioedema), Stevens-Johnson syndrome, cutaneous vasculitis, severe skin adverse reactions (rash, exfoliative skin disease), acute pancreatitis (fatal/non-fatal hemorrhagic or necrotizing), acute renal failure, severe and disabling arthralgia, bullous pemphigoid, rhabdomyolysis, anaphylaxis, angioedema, chest tightness, difficulty breathing, cold sweat, pallor, high fever accompanied by severe

Mild side effects

• Nasopharyngitis
• upper respiratory infection
• headache
• constipation
• vomiting
• myalgia
• limb pain
• back pain
• pruritus
• thrombocytopenia

This medication should be stored in a tightly sealed container to prevent air exposure and maintained at a temperature between 1 to 30 degrees Celsius for safety. Storing it this way will help maintain the medication's effectiveness.

Appearance

Light apricot colored, biconvex, round, film-coated tablets

Package unit

28 tablets/box [14 tablets/PTPX2]