Pariem Tablet 10 mg (Empagliflozin)

Adult dose

The recommended dose for this medication is 10 mg once daily for monotherapy and additional combination therapy with insulin and other antidiabetic agents. In cases with excellent tolerability and the need for additional blood sugar control, the dose may be increased to 25 mg once daily. This medication can be taken regardless of meals, and the tablet should be swallowed whole. Do not take double the prescribed dose in one day.

This medication should not be administered to certain patients. For example, patients with allergies to the active ingredient or components of this medication, patients with type 1 diabetes or diabetic ketoacidosis, patients with severely impaired kidney function, and those with genetic issues such as lactose intolerance or galactose absorption problems should not use this medication. In patients with moderately impaired kidney function, caution should be exercised, and if kidney function continues to deteriorate, discontinuation of this medication may be necessary. This medication is not expected to be effective in patients with end-stage renal disease or those undergoing dialysis. In patients with heart failure, especially those with mild to moderate cases, careful use is advised, and it is not recommended for severe heart failure patients. This medication may increase the risk of hypoglycemia when used with insulin or sulfonylureas, thus necessitating dose adjustments of these medications. While taking this medication, patients should carefully monitor for symptoms such as hypoglycemia, urinary tract infections, genital infections, increased urination, and decreased fluid volume. Especially, there is a risk of metabolic acidosis known as ketoacidosis, so if symptoms such as nausea, vomiting, abdominal pain, or difficulty breathing occur, immediate consultation with medical personnel is necessary. Elderly patients, especially those over 75 years of age, are at an increased risk of fluid volume loss, and caution is required when using this medication. This medication may affect kidney function, so regular kidney function tests are recommended. Additionally, this medication may have a mild impact when driving or operating machinery, so caution should be taken, especially in cases where there is a risk of hypoglycemia. Pregnant or breastfeeding women are advised to avoid taking this medication and should discontinue use upon confirmation of pregnancy. Safety and efficacy in children and adolescents under 18 years of age have not been established. No specific toxic symptoms have been reported in cases of overdose, but appropriate treatment may be required depending on the clinical condition. Lastly, this medication should be stored out of reach of children, and transferring it to another container may affect its quality.

Serious side effects

• Hives
• angioedema
• ketoacidosis
• urosepsis
• pyelonephritis
• perineal necrosis
• acute cholecystitis
• liver dysfunction (jaundice)
• acute kidney injury
• deep vein thrombosis

Mild side effects

• Hypoglycemia
• vulvovaginal candidiasis
• balanitis
• genital infections
• increased urination
• urination difficulties
• itching
• rash
• increased serum lipids
• increased serum creatinine

This medication should be stored in a sealed container to protect it from air or moisture and is best kept at room temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the medication's efficacy and safety.

Appearance

Pale yellow, double-convex, round film-coated tablet

Package unit

30 tablets / bottle