Sitavia 50 mg Tablets (Sitagliptin Hydrochloride Monohydrate)

Adult dosage

The medication is administered as 100 mg once daily for monotherapy or in combination therapy, with a maximum daily dosage of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dosage adjustment may be necessary according to renal function. In patients with mild to moderate renal impairment (eGFR ≥ 45 and < 60 mL/min/1.73 m2), no dosage adjustment is necessary. In patients with moderate renal impairment (eGFR ≥ 30 and <

This medication may cause hypersensitivity reactions; if symptoms such as skin rash, itching, or difficulty breathing develop after administration, consult a physician immediately. This medication can induce acute pancreatitis; therefore, if symptoms such as abdominal pain, nausea, or vomiting occur, notify healthcare personnel immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis. It should not be administered if there is a history of allergy or hypersensitivity to this medication or its ingredients. Patients with impaired renal function should have their dosage adjusted and should undergo regular renal function tests. Since hypoglycemia may occur when this medication is used alone or in combination with other diabetes therapies, blood glucose changes should be closely monitored. Particular caution is needed if used with insulin or sulfonylurea drugs as the risk of hypoglycemia may increase. If severe joint pain or movement limitations occur, stop taking this medication and consult a physician. If any bullous skin diseases, skin rashes, or urticaria develop, discontinue medication immediately and seek dermatological care. This medication is not recommended for pregnant or nursing women, and safety has not been established for children under 18 years of age. In elderly patients, renal function may decline, thus dosage adjustment and regular kidney function testing are necessary. There are relatively fewer drug interactions when used with other medications, but caution is needed when taken with certain drugs, so it is important to inform a physician or pharmacist. In case of overdose, seek medical attention immediately for appropriate treatment, and if necessary, the drug may be removed by dialysis.

Serious side effects

• Urticaria
• angioedema
• anaphylaxis
• Stevens-Johnson syndrome
• exfoliative dermatitis
• acute pancreatitis
• severe hypoglycemia
• acute renal failure
• severe and disabling arthralgia
• bullous pemphigoid

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• diarrhea
• nausea
• constipation
• myalgia
• limb pain
• back pain
• pruritus

Store this medication in a tightly closed container that allows for good air circulation, and keep at room temperature between 1°C and 30°C. This will help maintain the drug's effectiveness for a longer period.

Appearance

Bright yellow-orange round film-coated tablets

Package unit

100 tablets/bottle, 30 tablets/bottle