Medication info
Tobajet Tablets 10/20 Milligrams

Tobajet Tablets 10/20 Milligrams

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium Trihydrate›21.7mg / 1 tabletEzetimibe›10mg / 1 tablet
Manufacturer / importer
유니메드제약(주)
Appearance
A film-coated tablet in a capsule shape that is white or light yellow, with a biconvex surface on both sides.
Packaging
30 tablets/box (10 tablets/Alu-Alu×3)
Approval status
Active

MFDS item code 202101902 · Approved 2021.02.26 · Insurance code 649508080

Summary

Main use
Reduction of cholesterol in patients with hypercholesterolemia (primary, homozygous familial) and dyslipidemia, and mitigation of the risk of cardiovascular disease through increased HDL.
Who uses it
Adults
Adult dosage
This medication is administered once daily regardless of meal timing. For primary hypercholesterolemia, the dose range is 10/10mg to 10/80mg per day. The recommended initial dose is 10/10mg or 10/20mg once daily. For patients requiring more than a 55% reduction in LDL cholesterol, an initial dose of 10/40mg per day is recommended. After starting treatment or adjusting the dose, lipid levels should be checked at intervals of more than 2 weeks.

Ingredients

Manufacturer
유니메드제약(주)

Efficacy & effects

Reduction of cholesterol in patients with hypercholesterolemia (primary, homozygous familial) and dyslipidemia, and mitigation of the risk of cardiovascular disease through increased HDL.

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • dyslipidemia
View approved original text

This medication helps lower total cholesterol, LDL cholesterol, Apo B proteins, triglycerides, and non-HDL cholesterol levels while increasing HDL cholesterol in patients with primary hypercholesterolemia. Additionally, it effectively controls lipid levels in patients with homozygous familial hypercholesterolemia when used alone or in combination with other therapies. This medication is recommended to be used alongside a proper diet and in cases where non-drug therapies are insufficiently effective. It should be administered with careful consideration of the patient's overall risk factors, and it is crucial to check various lipid levels before treatment. By consistently taking this medication, lipid abnormalities can be improved, thereby reducing the risk of cardiovascular disease.

Dosage and Administration

Adult dosage

This medication is administered once daily regardless of meal timing. For primary hypercholesterolemia, the dose range is 10/10mg to 10/80mg per day. The recommended initial dose is 10/10mg or 10/20mg once daily. For patients requiring more than a 55% reduction in LDL cholesterol, an initial dose of 10/40mg per day is recommended. After starting treatment or adjusting the dose, lipid levels should be checked at intervals of more than 2 weeks.

Precautions

This medication may cause severe muscle problems, so patients should inform their physician immediately of any sudden muscle pain or weakness accompanied by fever. Patients with severe infections, hypotension, major surgeries or trauma, or uncontrolled seizures should temporarily discontinue or stop this medication. Furthermore, individuals with allergies to this medication, liver disease, muscle disorders, or women who are pregnant or breastfeeding should not take this medication. Patients with a history of alcohol dependence or compromised liver function, reduced kidney function, or hypothyroidism should also use caution. Taking this medication with certain other drugs may increase the risk of muscle damage, so it is essential to inform a doctor or pharmacist about any other medications being taken. Regular liver function tests should be conducted before and during treatment, and the medication should be discontinued immediately if symptoms of liver damage occur. This medication can elevate blood sugar levels, so patients at risk for diabetes should manage their blood sugar diligently. Dizziness or headaches may occur, requiring caution while driving or operating machinery. Women of childbearing potential should use appropriate contraceptive methods while taking this medication, and if pregnancy is confirmed, they should discontinue it immediately. The safety of this medication in children has not been established, hence it is not recommended. In case of overdose, there is no specific antidote, and treatment should be provided based on symptoms while monitoring liver function and muscle enzyme levels. This medication should be kept out of the reach of children, and it is advisable not to transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, painful mucous membranes in the mouth/eyes, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough+fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination problems

Mild side effects

  • Muscle pain
  • abdominal pain
  • elevated liver enzymes
  • dizziness
  • cough
  • nausea
  • vomiting
  • diarrhea
  • joint pain
  • muscle weakness
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  • musculoskeletal pain
  • hyperkalemia
  • bronchitis
  • sinusitis
  • flushing
  • headache
  • fatigue
  • malaise
  • chest pain
  • chest discomfort
  • swelling
  • asthenia
  • generalized edema
  • depression
  • bronchiolitis
  • dental abscess
  • vestibular neuritis
  • bradycardia
  • hypotension
  • anemia
  • hernia
  • vitamin D deficiency
  • gastric polyps
  • duodenal polyps
  • duodenitis
  • erectile dysfunction

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture, preferably at room temperature between 1°C and 30°C. Storing it this way will help maintain the efficacy of the medication over time.

Appearance and packaging

Appearance

A film-coated tablet in a capsule shape that is white or light yellow, with a biconvex surface on both sides.

Package unit

30 tablets/box (10 tablets/Alu-Alu×3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.