Ajet Tablet 10/20 mg

Adult dosage

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, a starting dose of 10/10 mg or 10/20 mg once daily is recommended. In patients who require more significant reductions in LDL cholesterol (over 55%), a starting dose of 10/40 mg once daily is recommended. After starting treatment or adjusting the dose, lipid levels should be checked after intervals of at least 2 weeks.

This medication can cause rare side effects that may affect the muscles, leading to a serious muscle damage known as rhabdomyolysis. In patients with acute infections, hypotension, major surgery or trauma, or severe endocrine disorders, this medication should be temporarily discontinued or its use reconsidered. It should not be administered to patients with an allergy to its components, active liver disease, muscle disorders, pregnant or breastfeeding women, or patients taking certain other medications. The medication should be used cautiously in patients with a history of alcohol abuse or liver disease, impaired renal function, or elderly patients, as they are at increased risk of muscle damage. This medication can affect liver function, so regular liver function tests should be performed before and during administration. Possible side effects include muscle pain, fatigue, abdominal pain, dizziness, cough, nausea, joint pain, muscle weakness, musculoskeletal pain, hyperkalemia, bronchitis, sinusitis, flushing, diarrhea, fatigue, malaise, headache, vomiting, constipation, indigestion, pharyngeal and laryngeal pain, nosebleeds, insomnia, nightmares, blurred vision, tinnitus, itching, rash, hair loss, thrombocytopenia, hepatitis, cholestasis, urticaria, skin rash, skin ulcer, sweating, and facial flushing. If severe muscle pain or weakness occurs, especially with fever, the medication should be discontinued immediately and a doctor should be consulted. As this medication may interact with other medications, it is essential to inform a doctor or pharmacist of any other drugs being taken. Women of childbearing age should use appropriate contraception to avoid pregnancy while taking this medication and must discontinue it immediately if pregnancy is confirmed. Special care is needed for children and the elderly, and the safety in children has not been established, so it is not recommended. In the case of overdose, treatment and supportive care should be provided based on symptoms, and liver function and muscle-related tests should be conducted to verify the condition. This medication should be kept out of reach of children, and transferring it to another container should be avoided.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanying cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination issues

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• joint pain
• muscle weakness
• musculoskeletal pain
• hyperkalemia

This medication may be sensitive to air and humidity, so it should be stored in a tightly sealed container. The recommended storage temperature is at room temperature between 1 degree and 30 degrees Celsius. Storing it this way can help maintain the drugs' effectiveness for a long time.

Appearance

White oval film-coated tablet

Package unit

PTP - 30 tablets/box [10 tablets/PTP packaging (Alu-Alu)x3], bottle - 30 tablets/bottle