Sitamon Tablet 100 mg (Sitagliptin Hydrochloride Hydrate)

Adult dosage

This medication is administered once daily at a dose of 100 mg for both monotherapy and combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, no dosage adjustment is needed for mild to moderate renal impairment (glomerular filtration rate 45 mL/min/1.73 m2 to less than 60). In cases of moderate renal impairment (glomerular filtration rate 30 to less than 45), a dosage of 50 mg once daily is recommended.

This medication can cause severe allergic reactions; therefore, if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur after administration, discontinue use immediately and consult a physician. While taking this medication, serious symptoms of pancreatitis may occur, so if symptoms like abdominal pain, vomiting, or loss of appetite develop, seek medical attention promptly. Patients with type 1 diabetes or diabetic ketoacidosis should not use this medication. Patients allergic to this medication or its components should not take it. Patients with impaired kidney function may need to adjust their dosage of this medication, especially those with severe renal impairment, who should be treated at a lower dose. During treatment, mild adverse reactions such as general cold symptoms, headaches, and nasopharyngitis may occur. When taken with other blood sugar-lowering agents, particularly insulin or sulfonylureas, hypoglycemia may appear, requiring regular blood sugar monitoring and dosage adjustments as necessary. This medication can trigger severe joint pain or skin blistering disorders, so if these symptoms appear, inform a doctor immediately and discontinue use of the medication. It is advisable for pregnant or nursing women to avoid this medication, and safety in children and adolescents under 18 years has not been established. Elderly patients may have reduced kidney function, making dosage adjustment and renal function testing important. In cases of overdose, general emergency treatment is warranted, and in some instances, dialysis may be necessary to remove some of the medication. This medication has a low potential for interaction with other drugs, but caution is required when using it with certain medications, so consult a doctor or pharmacist about other medications being taken.

Serious side effects

Urticaria, severe swelling (angioedema), anaphylaxis, severe allergic reactions, exfoliative skin diseases including Stevens-Johnson syndrome, severe joint pain with disability, blistering similar to pemphigus, acute pancreatitis, elevated liver enzymes, acute renal failure, difficulty breathing, cardiac arrest, pneumonia, diabetic complications, metabolic acidosis, severe edema, hypoglycemia (severe and requiring treatment)

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• constipation
• vomiting
• headache
• muscle pain
• limb pain
• back pain
• dyspepsia
• dizziness

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, and should be kept at room temperature between 1 and 30 degrees Celsius. This will help maintain the effectiveness of the medication.

Appearance

A bright brown, round, biconvex film-coated tablet

Package unit

28 tablets/box [14 tablets/PTP * 2]