Trusita Tablets 100 Milligrams (Sitagliptin Hydrochloride Hydrate)

Adult dosage

The recommended dose is 100 mg once daily, either as monotherapy or in combination therapy, with a maximum daily dose of 100 mg. For patients with renal impairment, dosage adjustment is as follows: - Mild renal impairment (eGFR ≥ 60 and < 90 mL/min/1.73 m2): No dosage adjustment needed. - Moderate renal impairment (eGFR ≥ 45 and < 60 mL/min/1.73 m2): Dosage adjustment

This medication may cause severe allergic reactions after use, so if symptoms such as skin rash or difficulty breathing occur, you should stop taking it immediately and consult a doctor. While taking this medication, symptoms of pancreatitis such as severe abdominal pain, vomiting, and fever may appear, so you should inform healthcare professionals immediately if these symptoms occur. Patients with type 1 diabetes or diabetic ketoacidosis should not take this medication. If you have allergies to this medication or its components, you must not take it. Patients with impaired kidney function need to adjust the dosage of this medication, and regular kidney function tests are essential. Hypoglycemia may occur when this medication is used alone or in combination with other diabetes medications, so pay attention to hypoglycemic symptoms and adjust the dosage as needed. Long-term use may lead to side effects such as headache, upper respiratory infection, nasopharyngitis, diarrhea, nausea, abdominal pain, constipation, myalgia, limb pain, back pain, pruritus, thrombocytopenia, indigestion, dizziness, increased blood triglycerides, increased low-density lipoproteins, hyperglycemia, hypernatremia, erectile dysfunction, weight loss, and hypertension. This medication can be used in elderly patients, but care should be taken to determine the dosage considering the possibility of decreased kidney function. Women who are pregnant or breastfeeding should avoid taking this medication, and its safety and efficacy have not been established in children and adolescents, so it is not used in this population. There are few interactions between this medication and certain drugs, but caution is needed when taken with digoxin or cyclosporine, and it should be taken according to the healthcare professional's instructions. In case of overdose, immediately go to the hospital for appropriate treatment, as some may be removed by hemodialysis. If severe joint pain or blisters occur while taking this medication, stop taking it immediately and seek professional medical attention.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, paleness (severe allergic reaction), severe rash with high fever, blisters, painful mucous membranes of the mouth/eyes (severe skin adverse reaction), shortness of breath or difficulty breathing, asthma attacks, respiratory issues with coughing + fever (respiratory problems), yellowing of skin or eyes (jaundice), extreme lethargy (liver abnormalities), sudden and severe

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• myalgia
• limb pain
• back pain

This medication should be stored in a tightly closed container to prevent air exposure, and it is best kept at room temperature between 1 to 30 degrees Celsius. By storing it this way, the medication's efficacy can be maintained for a longer period.

Appearance

Light brown, round, double-convex film-coated tablets

Package unit

PTP - 28 tablets/box [(14 tablets/PTP×2)]