Yucita Tablet 100 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg as monotherapy or in combination therapy, with a maximum daily dosage of 100 mg. In cases of renal impairment, no dosage adjustment is necessary for mild to moderate renal impairment (glomerular filtration rate [eGFR] ≥ 45 mL/min/1.73 m²). For moderate renal impairment with a glomerular filtration rate between 30 and 45, administer 50 mg once daily.

This medication may cause allergic reactions; if symptoms such as skin rash or difficulty breathing occur, discontinue use immediately and consult a physician. Acute pancreatitis, a serious inflammatory condition of the pancreas, may develop, thus immediate medical attention is required if symptoms such as abdominal pain, nausea, or vomiting arise. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis. Avoid taking this medication if you have allergies to this drug or its components. Patients with impaired renal function should have their dosage adjusted and take the medication under a physician's guidance. Hypoglycemic symptoms may occur while using this medication, especially when taken with insulin or sulfonylureas, thus close monitoring of blood glucose levels is advised. If severe joint pain or skin blisters occur, consult a physician immediately and stop taking the medication. Pregnant or breastfeeding women are advised not to use this medication, and safety and effectiveness have not been established for children or adolescents under 18 years of age. Elderly patients may experience decreased renal function, necessitating dosage adjustments and regular renal function tests. In case of overdose, visit a hospital immediately for appropriate treatment, as this medication may be partially removed via hemodialysis. This medication generally does not interact significantly with other medications, but caution is necessary when taken with specific drugs, so consult healthcare providers. Report any unusual symptoms during use to healthcare providers and take appropriate measures.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, severe skin reactions (including rash, skin peeling, pain in the mucous membranes of the mouth/eyes), Stevens-Johnson syndrome, acute pancreatitis, difficulty breathing, severe and disabling joint pain, bullous pemphigoid, liver abnormalities (elevated liver enzymes, symptoms of jaundice), deterioration in kidney function (acute renal failure, need for dialysis), acute renal failure, severe swelling accompanied by high blood pressure

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• diarrhea
• nausea
• constipation
• muscle pain
• limb pain
• back pain
• pruritus

Store this medication in a tightly closed container that is protected from air, at a temperature between 1 and 30 degrees Celsius. Proper storage will maintain the drug's effectiveness and prevent degradation.

Appearance

Bright brown, circular, bilayered film-coated tablet

Package unit

28 tablets/box [14 tablets/PTP x 2]