Yushita Tablet 25 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

The drug is administered once daily at a dose of 100 mg for monotherapy or combination therapy, with a maximum daily dose of 100 mg. Dose adjustments are necessary based on kidney function. For patients with mild to moderate renal impairment (eGFR 45 to less than 90), dose adjustments are not required. For patients with moderate renal impairment (eGFR 30 to less than 45), a dose of 50 mg once daily is administered. For patients with severe renal impairment (eGFR 15 or more

This drug is used for the treatment of diabetes. Rarely, serious allergic reactions may occur; if symptoms such as skin rash or difficulty in breathing appear, you must immediately stop taking the drug and consult a physician. Additionally, this drug may cause pancreatitis, so if symptoms such as abdominal pain, vomiting, or loss of appetite occur, please inform medical personnel immediately. It should not be used in patients with type 1 diabetes, diabetic ketoacidosis, or hypersensitivity to this drug or its components. Patients with impaired kidney function may have increased drug concentrations, so dosage adjustment is necessary; regular kidney function tests are recommended. Hypoglycemic symptoms may occur during the use of this drug, so particularly when taking it with insulin or sulfonylureas, blood sugar should be regularly checked and precautions for hypoglycemia are necessary. Rarely, side effects such as arthralgia or skin blisters may occur, so if severe joint pain or skin abnormalities are present, notify a doctor immediately. It is not recommended for pregnant or breastfeeding women, or children under 18 as its safety has not been established. In case of overdose, general emergency treatment should be received, and if necessary, some drugs may be removed by dialysis. This drug has relatively few drug interactions, but caution is needed when taking certain medications, so inform your doctor if you are taking other medications. Elderly patients may have decreased kidney function, so dosage adjustment and kidney function tests are necessary. Regular checks on health status should be conducted during the use of this drug, and if unusual symptoms appear, consult medical personnel immediately.

Serious side effects

Urticaria, severe swelling (angioedema), rash, exfoliative skin disease (Stevens-Johnson syndrome), chest tightness, difficulty breathing, cold sweat, pallor (severe allergic reaction), severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain (severe skin abnormal reactions), difficulty breathing or shortness of breath, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), very.

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• constipation
• vomiting
• myalgia
• limb pain
• back pain
• pruritus
• thrombocytopenia

This drug should be stored in a tightly sealed container to prevent air from entering, with the storage temperature maintained between 1 to 30 degrees Celsius at room temperature. By storing it this way, the drug's effectiveness can be well preserved, and deterioration can be prevented.

Appearance

Pink, round, biconvex film-coated tablets

Package unit

28 tablets/box [14 tablets/PTP X 2]