Abazet Tablets 10/20 mg

Adult dosage

This medicine is administered once daily regardless of meals. For primary hypercholesterolemia, an initial dose of 10/10 mg or 10/20 mg per day is recommended. For patients requiring a greater reduction in LDL cholesterol (55% or more), an initial dose of 10/40 mg per day is recommended. After starting treatment or adjusting the dose, blood lipid levels should be checked after an interval of more than 2 weeks.

This medicine can cause muscle-related issues such as severe muscle pain or weakness and, in rare cases, acute renal failure due to serious muscle damage known as rhabdomyolysis. Therefore, if symptoms of serious myopathy occur or if there is a high risk of muscle damage, the use of this medicine should be temporarily or permanently discontinued. This medicine should not be administered to patients with allergies to certain ingredients, those with active liver disease or persistently elevated liver enzyme levels of unknown cause, patients with muscle disorders, pregnant or nursing women, patients taking certain antiviral medications, and those with lactose intolerance. Alcoholics, individuals with a history of liver disease, those with severe liver dysfunction, those with poor kidney function or hypothyroidism, individuals with a family history of genetic muscle disorders, and the elderly are at higher risk of muscle damage and should use this medicine cautiously. Additionally, caution is needed for patients taking fibrate-class medications or those exhibiting severe muscle weakness symptoms. Adverse reactions such as muscle pain, abdominal pain, elevated liver enzymes, dizziness, cough, nausea, diarrhea, joint pain, muscle weakness, musculoskeletal pain, hyperkalemia, bronchitis, sinusitis, flushing, fatigue, malaise, chest pain, chest discomfort, swelling, weakness, generalized edema, headache, urticaria, rash, pruritus, hair loss, skin nodules, tinnitus, blurred vision, vomiting, dry mouth, epigastric discomfort, belching, gastrointestinal disturbances, and gastroesophageal reflux disease may occur during the use of this medicine; in severe cases, medication discontinuation may be necessary. Liver function tests are required, and if symptoms of liver damage occur, immediate consultation with a physician is necessary. Pregnant or potentially pregnant women should not take this medicine and should use appropriate contraception while on this medication. Symptoms such as dizziness may occur, so caution is needed when driving or operating machinery. This medicine may interact with other medications, so if taking other drugs, consult a physician or pharmacist. Safety in children has not been established, so use is not recommended. The elderly are also at risk for myopathy and should be cautious while taking this medicine, and dose adjustments may be necessary for patients with poor liver or kidney function. In case of overdose, there is no specific antidote, so symptomatic treatment and supportive care are required, and liver function and muscle-related tests should be performed regularly.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headache, lightning-like headache, seizures, confusion, visual abnormalities, paralysis, urination.

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain

This medicine should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius to safely preserve its effectiveness.

Appearance

A film-coated tablet in the shape of a capsule, white or pale yellow, with both sides convex.

Package unit

30 tablets/box [10 tablets/Alu-Alu X 3]