Atovanjett Tablet 10/10 mg

Adult dosage

This medication is administered once daily regardless of meals. The dosage range for primary hypercholesterolemia is 10/10 mg to 10/80 mg per day. Initial doses of 10/10 mg or 10/20 mg per day are recommended. For patients requiring greater reductions in LDL cholesterol (more than 55%), an initial dose of 10/40 mg per day is recommended. After starting treatment or adjusting the dose, lipid levels should be checked at intervals of more than 2 weeks.

This medication has been associated with a rare side effect known as rhabdomyolysis, which can cause severe muscle damage. This side effect may lead to acute renal failure, so it is important to immediately inform a physician if severe muscle pain or weakness occurs. Patients with severe infections, hypotension, major surgery or trauma, severe metabolic disorders, or uncontrolled seizures may need to temporarily discontinue this medication. Patients with allergies to any ingredients in this medication, as well as those with liver disease, muscle disease, and women who are pregnant or breastfeeding should not use this medication. Additionally, patients with certain antiviral therapy or lactose intolerance should also avoid administration. Careful use of this medication is necessary for patients with alcohol addiction, poor liver function, kidney issues, thyroid dysfunction, and elderly patients. Patients at risk for myopathy should have muscle enzyme levels checked before administration and monitored regularly during treatment. Since there are several medications that may interact with this drug, it is essential to inform healthcare providers of any medications being taken. Liver function tests should also be conducted regularly during treatment, and administration should be discontinued immediately if symptoms of liver damage appear. Women who are pregnant or may become pregnant must use adequate contraception while taking this medication and discontinue it immediately if pregnancy is confirmed. Caution is required during driving or operating machinery as dizziness may occur. The safety and effectiveness of this medication in children have not been established and it is not recommended.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty in breathing, asthma attack, respiratory difficulties accompanied by cough and fever, skin or eye yellowing (jaundice), notable lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, fainting

Mild side effects

• Muscle pain
• abdominal pain
• dizziness
• nausea
• constipation
• diarrhea
• joint pain
• musculoskeletal pain
• hyperkalemia
• bronchitis

This medication should be stored in a tightly closed container to protect it from air and moisture. It is recommended to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

White, biconvex, oblong film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP*3]