Lipitajet Tablet 10/20 mg

Adult dosage

This medication is taken once daily, regardless of meals. For primary hypercholesterolemia, the recommended starting dose is 10/10 mg or 10/20 mg once daily, and for patients requiring a greater reduction in LDL cholesterol (55% or more), the recommended starting dose is 10/40 mg once daily. The recommended dosage for patients with homozygous familial hypercholesterolemia is 10/40 mg or 10/80 mg once daily. Initiation of therapy

This medication may rarely but severely cause muscle damage known as rhabdomyolysis; therefore, patients should notify their doctor immediately if they experience muscle pain, weakness, fatigue, or fever. This medication can affect liver function; therefore, liver function tests should be conducted before administration, and if symptoms of liver dysfunction appear during treatment, immediate medical attention is required. This medication should not be administered to patients with certain liver diseases or muscle disorders, pregnant women or those who may become pregnant, nursing mothers, and patients taking specific medications. It is advisable to avoid or limit alcohol intake during treatment, especially for patients with a history of liver disease. This medication may interact with other drugs; therefore, patients should inform their doctor or pharmacist about all medicines they are taking, especially when used with CYP3A4 inhibitors, fibrates, antiviral agents, antibiotics, and immunosuppressants. Regular blood tests should be conducted to monitor liver function and muscle enzyme levels during treatment, and dosage adjustments or discontinuation may be necessary if abnormal findings are noted. This medication is not recommended for children as safety and efficacy have not been established, and caution is required when used in elderly patients due to the risk of myopathy. Patients should be cautious when driving or operating machinery as dizziness may occur. In case of overdose, there is no specific antidote; therefore, immediate medical attention should be sought to receive appropriate treatment and supportive care. Finally, this medication should be kept out of the reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attack, respiratory distress with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination changes

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• joint pain
• muscle weakness
• musculoskeletal pain
• hyperkalemia

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is best stored at room temperature between 1°C and 30°C, avoiding excessively hot or cold areas.

Appearance

White, rectangular film-coated tablet

Package unit

30 tablets/box (10 tablets/PTP packaging (Alu-Alu) * 3), 30 tablets/bottle, 100 tablets/bottle