Lipiduet Tablets 10/20 mg (Ezetimibe, Atorvastatin Calcium Trihydrate)

Adult dosage

This medication is taken once daily, regardless of meals. For primary hypercholesterolemia, an initial dose of 10/10 mg or 10/20 mg is recommended. For patients requiring a greater reduction in LDL-cholesterol (more than 55%), an initial dose of 10/40 mg is suggested. After starting the treatment or adjusting the dosage, blood lipid levels should be checked at intervals of more than 2 weeks to adjust the dosage accordingly.

This medication is used to lower blood cholesterol levels and works by combining two components for effect. Before taking this drug, it is crucial to inform your doctor immediately if there is severe muscle pain or weakness. This can lead to rare but serious muscle damage (rhabdomyolysis). If you have liver function issues or a history of liver disease, taking this drug may worsen liver damage, so caution is necessary. Regular liver function tests before and during treatment are essential. This medication may interact with certain drugs, so if you are currently taking any medications, be sure to inform your healthcare provider. It is particularly important when taken with drugs metabolized by the liver. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication and should use appropriate contraceptive methods while on it. Elderly patients or those with impaired kidney function may have an increased risk of muscle damage, thus they should strictly follow physician instructions during treatment. In the event of an overdose, there is no specific antidote, so treatment should be symptomatic with monitoring of liver function and muscle status. If dizziness, muscle pain, or abdominal pain occurs during treatment, consult your healthcare provider immediately, and if symptoms are severe, discontinue use. This medication is not recommended for children as safety and efficacy have not been established. Store this medication out of reach of children, and it is advisable to avoid transferring it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rashes with high fever, blisters, skin peeling, oral/eye mucosal pain, shortness of breath or trouble breathing, asthma attacks, respiratory distress accompanied by cough + fever, jaundice (skin or eyes turning yellow), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination changes

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain

This medication should be stored in a tightly closed container to prevent exposure to air and moisture. It is best kept at room temperature between 1 to 30 degrees Celsius, away from excessive heat or cold.

Appearance

White or pale yellow, biconvex film-coated tablets in capsule shape

Package unit

30 tablets/box [(10 tablets/Alu-Alu x 3)]