Lipiduet Tablet 10/10 mg (Ezetimibe, Atorvastatin Calcium)

Adult dosage

This medication is taken once daily, regardless of meals. The dosage range for primary hypercholesterolemia is 10/10 mg to 10/80 mg per day, with a recommended initial dose of 10/10 mg or 10/20 mg per day. For patients requiring significant LDL cholesterol reduction (55% or more), an initial dose of 10/40 mg per day is recommended. After initiation of treatment or dose adjustment, follow-up of lipid levels should be done at intervals of more than 2 weeks.

This medication is a drug that helps lower blood cholesterol levels, with the active ingredients being Ezetimibe and Atorvastatin Calcium. Before taking this medication, if symptoms such as muscle pain, muscle weakness, or muscle cramps occur, inform your doctor immediately. These symptoms can rarely progress to a serious muscle damage condition called rhabdomyolysis, which may lead to kidney problems. In cases of severe infections, hypotension, major surgery, trauma, severe metabolic disorder, or uncontrolled seizures, the use of this medication may need to be temporarily paused or stopped. Patients with a known allergy to any of the ingredients in this medication, those with active liver disease, or those with persistently elevated liver enzyme levels of unknown cause, or patients with muscle diseases should not use this medication. Women who are pregnant, may become pregnant, or are breastfeeding should not take this medication, and women of childbearing potential should use appropriate contraception while taking it. This medication may affect liver function, so regular liver function tests should be performed before and during treatment, and if symptoms of liver dysfunction occur, inform your doctor immediately. This medication can interact with other drugs; thus, if you are currently taking any medications, be sure to inform your doctor or pharmacist. Caution is especially needed when taken with certain antibiotics, antiviral agents, antifungals, immunosuppressants, or fibrate medications. Elderly patients or those with diminished kidney function may have an increased risk of developing myopathy, so caution is advised during use. In case of overdose, there is no specific antidote, so treatment should be symptom-based and supportive, and liver function along with muscle enzyme levels should be monitored. Dizziness or fatigue may occur, so caution should be observed when driving or operating machinery. The safety and efficacy of this medication in children have not been established, so it is not recommended for use in pediatric patients. For safe storage, this medication should be kept out of reach of children, and it is advisable not to transfer it to other containers.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, cough+fever accompanied breathing abnormalities, yellowing of skin or eyes (jaundice), severe lethargy, sudden and severe headache, lightning headache, seizures, confusion, visual abnormalities, paralysis, urination problems

Mild side effects

• Muscle pain
• abdominal pain
• dizziness
• headache
• nausea
• diarrhea
• fatigue
• joint pain
• muscle weakness
• musculoskeletal pain

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained at room temperature between 1°C and 30°C. This helps to preserve the medication's effectiveness and safety for a longer time.

Appearance

White or pale yellow, round, film-coated tablet with a biconvex shape

Package unit

30 tablets/box [10 tablets/Alu-Alu x 3]