Medication info
AtorMJet Tablets 10/40 mg

AtorMJet Tablets 10/40 mg

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium Trihydrate›43.4mg / 1 tabletEzetimibe›10mg / 1 tablet
Manufacturer / importer
(주)마더스제약
Appearance
White oblong film-coated tablet
Packaging
30 tablets/Alu-Alu[(10 tablets/Alu-Alu x 3)]
Approval status
Active

MFDS item code 202101648 · Approved 2021.02.18 · Insurance code 622804510

Summary

Main use
Reduction of cholesterol and increase of HDL in primary hypercholesterolemia (homozygous familial) and dyslipidemia, thereby mitigating the risk of cardiovascular disease.
Who uses it
Adults
Adult dosage
This medication is taken once daily, regardless of meals. For primary hypercholesterolemia, it is administered within the range of 10/10 mg to 10/80 mg daily, with an initial dose of 10/10 mg or 10/20 mg recommended. For patients who require more substantial reductions in LDL cholesterol, an initial dose of 10/40 mg daily is preferred. After initiation of treatment or dose adjustment, lipid levels should be checked after an interval of at least 2 weeks.

Ingredients

Manufacturer
(주)마더스제약

Efficacy & effects

Reduction of cholesterol and increase of HDL in primary hypercholesterolemia (homozygous familial) and dyslipidemia, thereby mitigating the risk of cardiovascular disease.

  • Primary hypercholesterolemia
  • dyslipidemia
  • homozygous familial hypercholesterolemia
  • increased risk of atherosclerotic vascular disease due to hypercholesterolemia.
View approved original text

This medication helps lower high cholesterol and triglyceride levels in patients with primary hypercholesterolemia and mixed dyslipidemia, and increases good cholesterol (HDL). Additionally, it is used as an adjunct to other treatments in patients with homozygous familial hypercholesterolemia or when other treatments are ineffective. This medication aids in controlling lipid levels for individuals at high risk of cardiovascular disease and should be used alongside a proper diet. It is crucial to check and treat any secondary causes and perform appropriate lipid testing and treatment for the patients who need it. This helps effectively manage hypercholesterolemia and dyslipidemia.

Dosage and Administration

Adult dosage

This medication is taken once daily, regardless of meals. For primary hypercholesterolemia, it is administered within the range of 10/10 mg to 10/80 mg daily, with an initial dose of 10/10 mg or 10/20 mg recommended. For patients who require more substantial reductions in LDL cholesterol, an initial dose of 10/40 mg daily is preferred. After initiation of treatment or dose adjustment, lipid levels should be checked after an interval of at least 2 weeks.

Precautions

This medication has been reported to cause a rare side effect called rhabdomyolysis, which can lead to severe muscle damage. Consequently, kidney function may deteriorate rapidly, and immediate consultation with a doctor should occur if severe muscle pain or weakness appears. This medication should not be used in patients with specific diseases, pregnant women, or patients taking particular medications. For example, patients with severely impaired liver function, muscle diseases, and those who are pregnant or breastfeeding should not take this medication. Individuals with a history of alcohol addiction or liver disease, those with impaired kidney function, patients with hypothyroidism, and the elderly should be especially cautious with this medication. These patients may have an increased risk of muscle damage, thus careful consumption under a physician's guidance is essential. This medication can affect liver function, so regular liver function tests should be performed before and during treatment. If abnormalities in liver function are detected, dose adjustments or discontinuation of the medication may be necessary. This medication can interact with several other drugs, so patients must inform healthcare providers about any other medications they are taking. Particularly, the risk of muscle damage may increase when used in combination with certain antibiotics, antivirals, antifungals, or immunosuppressants. Women of childbearing age should use appropriate contraception to prevent pregnancy while taking this medication, and should discontinue its use and consult a doctor immediately if pregnancy is confirmed. Symptoms such as dizziness, muscle pain, and fatigue may occur, so caution is necessary when driving or operating machinery. There is no specific antidote for overdose, so appropriate treatment should be received based on symptoms, and liver function and muscle status should be monitored. This medication is not recommended for children due to established safety and efficacy not being confirmed, and caution is advised for the elderly regarding the risk of muscle damage, though dose adjustments are generally not required. When taking this medication, it is crucial to follow the doctor’s prescription and instructions, and immediately consult healthcare professionals if any unusual symptoms occur.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, jaundice, extreme lethargy, sudden severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis.

Mild side effects

  • Muscle pain
  • abdominal pain
  • elevated liver enzymes
  • dizziness
  • cough
  • nausea
  • joint pain
  • muscle weakness
  • musculoskeletal pain
  • hyperkalemia
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  • bronchitis
  • sinusitis
  • flushing
  • increased ALT
  • increased AST
  • fatigue
  • lethargy
  • chest pain
  • weakness
  • constipation
  • diarrhea
  • loss of appetite
  • vomiting
  • dyspepsia
  • belching
  • pancreatitis
  • throat pain
  • nosebleed
  • insomnia
  • nightmares
  • headache
  • abnormal sensation
  • numbness
  • dysgeusia
  • memory loss
  • peripheral neuropathy.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is best to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

White oblong film-coated tablet

Package unit

30 tablets/Alu-Alu[(10 tablets/Alu-Alu x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.