Ladojet Tablets 10/20 mg

Adult dosage

This medication is administered once daily regardless of meals. For initial dosing in primary hypercholesterolemia, 10/10 mg or 10/20 mg per day is recommended. For patients requiring greater reductions in LDL cholesterol (over 55%), an initial dose of 10/40 mg per day is recommended. After initiating treatment or adjusting dosage, blood lipid levels should be checked at intervals of more than 2 weeks before adjusting the dose.

This medication may cause rhabdomyolysis, a rare side effect that can affect the muscles. As this may lead to renal function issues, immediate consultation with a doctor is required if severe muscle pain or weakness occurs. This medication should not be used in patients with certain conditions, such as those with liver disease or muscle disorders, pregnant or breastfeeding women, and those taking specific medications. Patients with a history of alcohol dependence, impaired liver function, and elderly individuals with a high risk of myopathy need to be particularly cautious when using this medication and should regularly assess their muscle condition and have blood tests performed. Liver function abnormalities may occur during the use of this medication, thus requiring monitoring of liver function tests and symptoms. Medication may need to be discontinued if abnormal symptoms relating to the liver appear. This medication can interact with other drugs, so it is crucial to inform the doctor or pharmacist about any medications currently being taken. Caution is particularly needed when taken along with certain antibiotics, antivirals, and anticoagulants. Women who are pregnant or planning to become pregnant should not take this medication, and fertile women should exercise appropriate contraception. Breastfeeding women are also advised to avoid taking this medication. Safety and efficacy in pediatric patients have not been established, hence it is not recommended for children. In the case of overdose, there is no specific antidote, and appropriate treatment and supportive therapy should be provided based on symptoms while monitoring liver function and muscle enzyme levels. Symptoms such as dizziness or muscle pain may occur while taking this medication, so caution is advised when driving or operating machinery.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Muscle pain
• abdominal pain
• headache
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• musculoskeletal pain
• hyperkalemia

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. Additionally, it is best stored at a cool room temperature, protected from direct sunlight, ideally between 1°C and 30°C.

Appearance

White rectangular film-coated tablet

Package unit

30 tablets/Alu-Alu[(10 tablets/Alu-Alu x3)]