Jetistone Tablet 10/40 mg

Adult dosage

This medication is administered once daily regardless of meals. The dosage range is 10/10 mg to 10/80 mg per day. A starting dose of 10/10 mg or 10/20 mg per day is recommended. For patients requiring a greater (55% or more) reduction in LDL cholesterol, a starting dose of 10/40 mg per day is recommended. After initiating treatment or adjusting the dose, blood lipids should be checked at intervals of more than two weeks.

This medication can rarely cause a serious condition known as rhabdomyolysis, which may lead to a rapid decline in kidney function. Therefore, if severe muscle pain or weakness occurs, it is necessary to consult a doctor immediately. This medication should not be used in certain patients, particularly those with poor liver function or muscle disorders, women who are pregnant or may become pregnant, patients with certain liver diseases, and those taking specific other medications. Patients with a history of alcoholism or liver disease, those with impaired kidney function, elderly patients, and others at high risk of muscle complications should use this medication cautiously and require regular monitoring. Since this medication may cause liver function abnormalities, it is important to conduct liver function tests and monitor for symptoms. If symptoms such as nausea, vomiting, fatigue, or jaundice appear, inform a doctor immediately. This medication may elevate blood sugar levels; therefore, patients at risk for diabetes should manage their blood sugar carefully. Women who are pregnant or breastfeeding should not take this medication, and women of childbearing age should use appropriate contraception during treatment. Side effects such as dizziness or muscle pain may occur, so caution is required when driving or operating machinery. This medication has many drug interactions, and the risk of muscle injury may increase if taken with certain drugs, so all medications being taken should be communicated to a physician. There is no specific antidote for overdose; treatment should be symptom-based with monitoring of liver function and muscle enzymes. This medication is not recommended for children as safety and efficacy have not been established. During treatment with this medication, if symptoms such as muscle pain, fatigue, or fever occur, inform a doctor immediately and undergo necessary testing. Also, if liver function abnormalities are suspected, discontinue use and consult a physician.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral or ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, lightning type headache, seizures, altered consciousness, visual disturbances, paralysis, urinary retention

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain

This medication should be kept in a tightly closed container to prevent air or moisture from entering and should be stored in a cool place below 30 degrees Celsius. Storing it this way will help maintain its effectiveness for a longer time.

Appearance

White to off-white, double convex oval film-coated tablets

Package unit

30 tablets/box [10 tablets/PTPX3]