Atovastatin Plus Tablets 10/20mg (Ezetimibe, Atorvastatin Calcium Trihydrate)

Adult dosage

This medication is administered once daily, irrespective of meals. The dosage range for this medication is 10/10mg to 10/80mg per day. An initial dose of 10/10mg or 10/20mg per day is recommended. For patients requiring a greater reduction in LDL cholesterol (over 55%), an initial dose of 10/40mg per day is advised. After starting treatment or adjusting the dosage, blood lipid levels should be monitored at intervals of more than 2 weeks.

This medication poses a risk of muscle-related issues, so if severe muscle pain or weakness occurs, it should be reported to a physician immediately. Patients with severe infections, low blood pressure, significant surgeries or trauma, or severe metabolic disorders may need to temporarily discontinue or stop this medication. This medication should not be used by those allergic to the active ingredients or other components, those with severely impaired liver function, individuals with muscle disorders, pregnant or nursing women, those taking specific antiviral medications, or individuals with lactose intolerance. Caution should be exercised when administered to alcoholics, individuals with a history of liver disease, those with compromised kidney function, patients with hypothyroidism, those with a family history of muscle disorders or previous muscle toxicity reactions, and seniors aged 70 years and older. Regular liver function and muscle-related tests should be performed during treatment, and if any abnormal symptoms arise, consultation with a physician should be sought immediately. When used in conjunction with other medications, the risk of side effects may increase due to interactions, so patients should inform their physician of any current medications. Women who are pregnant or may become pregnant should not take this medication and should discontinue it immediately and consult a physician if they are currently taking it. It is also recommended that nursing mothers avoid using this medication, consulting a physician if necessary. The safety and efficacy of this medication have not been established in children and it is not recommended for use. No special dosage adjustments are needed for the elderly, but attention should be paid to the possibility of muscle issues. In case of overdose, as there is no specific antidote, appropriate treatment and supportive care should be provided based on symptoms, and liver function and muscle status should be monitored regularly. This medication should be stored out of reach of children and should not be transferred to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, cough with fever and respiratory abnormalities, jaundice (yellowing of the skin or eyes), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues.

Mild side effects

• Muscle pain
• abdominal pain
• dizziness
• nausea
• headache
• fatigue
• diarrhea
• hyperkalemia
• bronchitis
• sinusitis

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. Additionally, avoid storing it in extremely hot or cold places, and it is best to keep it at room temperature between 1 degree and 30 degrees Celsius.

Appearance

White or whitish oblong film-coated tablets

Package unit

30 tablets/box [(10 tablets/Alu-Alu × 3)]