Atovagin Plus Tablets 10/40 mg (Ezetimibe, Atorvastatin Calcium Trihydrate)

Adult dosage

This medication is taken once daily regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg once daily, with starting doses of 10/10 mg or 10/20 mg recommended. If more LDL reduction is required, a starting dose of 10/40 mg per day is recommended. After starting treatment, lipid levels should be checked at intervals of more than 2 weeks.

This medication carries the risk of muscle problems, so if severe muscle pain or weakness occurs, consult a physician immediately. Particularly, serious muscle damage may cause kidney dysfunction, so caution is required for those with kidney diseases or other risk factors. Patients allergic to any ingredients in this medication or with severe liver problems, pregnant women, or lactating women should not take this medication. Patients taking certain medications or with genetic lactose intolerance should also avoid it. Caution is necessary for alcoholics, patients with severe liver dysfunction, and those with a history of muscle diseases while using this medication. Regular liver function tests must be conducted during treatment, and the medication may need to be stopped if liver enzyme levels are abnormally high. Elderly patients are at risk for myopathy, and caution is required when taking this medication, but dosage adjustment is typically not necessary. This medication may interact with other drugs, so inform your doctor or pharmacist if you are taking any other medications. Particular caution is advised when used in combination with certain antibiotics, antivirals, antifungals, etc., which may increase the risk of muscle damage. This medication can harm the fetus during pregnancy, so women of childbearing age should use appropriate contraception while taking it. It is also advisable to avoid this medication while breastfeeding, as there may be a possibility of adverse reactions during lactation. Caution is needed when driving or operating machinery due to possible side effects such as dizziness or muscle pain. In case of overdose, there is no specific antidote, so symptomatic treatment and supportive therapy should be administered. This medication is not recommended for children due to safety and efficacy not being established. Keep this medication out of the reach of children and avoid transferring it to another container as it may affect quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), severe general malaise, sudden and severe headache, thunderclap headache, seizures, confusion, vision changes, paralysis, urination

Mild side effects

• Dizziness
• cough
• abdominal pain
• nausea
• joint pain
• muscle weakness
• musculoskeletal pain
• hyperkalemia
• bronchitis
• sinusitis

This medication should be stored in a closed container to protect it from air or moisture. Additionally, the medication should be kept at room temperature, ideally between 1 to 30 degrees Celsius, without being too hot or too cold.

Appearance

White or off-white oval film-coated tablets

Package unit

30 tablets/box [(10 tablets/Alu-Alu × 3)]