Medication info
Amive Tablets 10/10 Milligrams

Amive Tablets 10/10 Milligrams

Prescription medicationTabletExpired
Ingredient · strength
Atorvastatin Calcium Trihydrate›10.85mg / 1 tabletEzetimibe›10mg / 1 tablet
Manufacturer / importer
(주)휴온스생명과학
Appearance
White to off-white, bilaterally convex oval film-coated tablet
Packaging
30 tablets/box - 10 tablets/Blister [X 3]
Approval status
Expired

MFDS item code 202101614 · Approved 2021.02.18

This product's status changed to Expired on 2026.02.18. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Lipid control effect through cholesterol reduction and HDL increase in hypercholesterolemia and dyslipidemia
Who uses it
Adults
Adult dosage
This medication should be administered once daily regardless of meals. For patients with primary hypercholesterolemia, a dosage range of 10/10mg to 10/80mg per day is prescribed, with a recommended starting dose of 10/10mg or 10/20mg daily. For patients requiring greater LDL cholesterol reduction, a starting dose of 10/40mg daily is recommended. After prescribing, lipid levels in the blood should be checked at intervals of no less than 2 weeks.

Ingredients

Manufacturer
(주)휴온스생명과학

Efficacy & effects

Lipid control effect through cholesterol reduction and HDL increase in hypercholesterolemia and dyslipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • elevated total cholesterol
  • elevated LDL cholesterol
  • elevated Apo B protein
  • elevated triglycerides
  • elevated non-HDL cholesterol
View approved original text

This medication is used as an adjunct to diet to lower total cholesterol, LDL cholesterol, Apo B, triglycerides, and non-HDL cholesterol levels while increasing HDL cholesterol levels in patients with familial or non-familial primary hypercholesterolemia and mixed dyslipidemia. It is also prescribed for patients with homozygous familial hypercholesterolemia when other lipid-lowering therapies are not effective or additional therapy is needed. This medication helps improve vascular health by controlling lipid levels in patients at increased risk of cardiovascular disease. However, prior to treating dyslipidemia, secondary causes such as diabetes, hypothyroidism, and liver disease should be identified and managed, and it should be used in conjunction with an appropriate diet for effectiveness. Regular lipid testing to monitor treatment efficacy is also important. Therefore, this medication is useful in the treatment of hypercholesterolemia and related dyslipidemia.

Dosage and Administration

Adult dosage

This medication should be administered once daily regardless of meals. For patients with primary hypercholesterolemia, a dosage range of 10/10mg to 10/80mg per day is prescribed, with a recommended starting dose of 10/10mg or 10/20mg daily. For patients requiring greater LDL cholesterol reduction, a starting dose of 10/40mg daily is recommended. After prescribing, lipid levels in the blood should be checked at intervals of no less than 2 weeks.

Precautions

This medication can cause a rare side effect that affects the muscles, known as rhabdomyolysis, so if severe muscle pain or weakness occurs, notify a doctor immediately. Particularly, patients with serious infections, hypotension, after major surgery, trauma, or metabolic disorders may need to temporarily halt or discontinue the administration of this medication. Patients allergic to any ingredients in this medication or those with liver disease, muscle disease, or women who are pregnant or breastfeeding should not take this medication. Caution should be exercised in individuals with a history of alcohol dependence, impaired liver function, reduced kidney function, hypothyroidism, or a family history of muscle-related diseases. This medication can affect liver function; therefore, liver function tests should be conducted before administration and monitored regularly during treatment. Side effects such as muscle pain, fatigue, headache, indigestion, and diarrhea may occur, so if symptoms are severe or persistent, inform healthcare professionals. This medication can interact with other drugs, so if you are taking any other medications, notify your healthcare provider, especially when combined with specific antibiotics, antivirals, or antifungal agents. Women of childbearing potential must use appropriate contraceptive methods to prevent pregnancy while taking this medication and should immediately discontinue use if pregnancy is confirmed. Dizziness may occur, so caution should be taken with driving or operating machinery while on this medication. The safety and effectiveness of this medication for children have not been established, and it is not recommended. In cases of overdose, there is no specific antidote, so treatment should be symptomatic with liver function and muscle-related examinations performed. Keep out of reach of children, and it is advisable not to transfer to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in the oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory difficulties accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

  • Muscle pain
  • abdominal pain
  • elevated liver enzymes
  • dizziness
  • cough
  • nausea
  • diarrhea
  • joint pain
  • muscle weakness
  • musculoskeletal pain
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  • hyperkalemia
  • bronchitis
  • sinusitis
  • flushing
  • fatigue
  • malaise
  • chest pain
  • headache
  • constipation
  • indigestion
  • vomiting
  • belching
  • pancreatitis
  • throat and larynx pain
  • nosebleed
  • insomnia
  • nightmares
  • sensory disturbances
  • taste disturbances
  • memory loss
  • peripheral neuropathy
  • itching
  • rash
  • hair loss
  • angioedema
  • erythema multiforme

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, and it is recommended to store it at a cool temperature below 30 degrees Celsius. This helps maintain the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

White to off-white, bilaterally convex oval film-coated tablet

Package unit

30 tablets/box - 10 tablets/Blister [X 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.