Medication info
Altjet Tablet 10/20 Milligrams

Altjet Tablet 10/20 Milligrams

Prescription medicationTablet
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›21.7mg / 1 tablet
Manufacturer / importer
영일제약(주)
Appearance
White or off-white oval-shaped film-coated tablet
Packaging
30 tablets/box [(10 tablets/Alu-Alu x 3)]
Approval status
Active

MFDS item code 202101598 · Approved 2021.02.18

Summary

Main use
Improvement of lipid levels by reducing cholesterol in hypercholesterolemia and dyslipidemia and increasing HDL.
Who uses it
Adults
Adult dosage
This drug is taken once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg per day. A starting dose of 10/10 mg or 10/20 mg daily is recommended. For patients requiring more significant LDL cholesterol reduction (over 55%), a starting dose of 10/40 mg daily is recommended. After initiation of treatment or dose adjustment, blood lipid levels should be checked at intervals of not less than two weeks.

Ingredients

Manufacturer
영일제약(주)

Efficacy & effects

Improvement of lipid levels by reducing cholesterol in hypercholesterolemia and dyslipidemia and increasing HDL.

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • dyslipidemia
  • increased risk of atherosclerotic vascular disease due to hypercholesterolemia.
View approved original text

In patients with primary hypercholesterolemia and mixed dyslipidemia, this drug helps lower elevated total cholesterol, LDL cholesterol, Apo B protein, triglycerides, and non-HDL cholesterol levels, and increases the level of good HDL cholesterol. Additionally, in patients with homozygous familial hypercholesterolemia, it can be used when other lipid-lowering treatments are ineffective or as an adjunct therapy. This drug is administered in conjunction with a dietary regimen and should be effectively complemented by non-pharmacological treatments such as restriction of saturated fats and cholesterol intake. It is also important to verify and treat the presence of other diseases or medications causing dyslipidemia as necessary. This drug assists in controlling cholesterol levels in patients at high risk for cardiovascular diseases, and thus, is used to improve dyslipidemia.

Dosage and Administration

Adult dosage

This drug is taken once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg per day. A starting dose of 10/10 mg or 10/20 mg daily is recommended. For patients requiring more significant LDL cholesterol reduction (over 55%), a starting dose of 10/40 mg daily is recommended. After initiation of treatment or dose adjustment, blood lipid levels should be checked at intervals of not less than two weeks.

Precautions

This drug may rarely cause serious side effects such as muscle disorders known as myopathy or rhabdomyolysis. In particular, patients with acute infections, hypotension, major surgery or trauma, endocrine disorders, etc., should temporarily suspend or discontinue the use of this drug. Those with allergies to the active ingredients or components of this drug, severely impaired liver function, muscle diseases, women who are pregnant or breastfeeding, and those taking certain other medications should not take this drug. Caution is advised for individuals with a history of alcoholism or liver disease, those with poor kidney function or hypothyroidism, and the elderly, who are at higher risk for muscle issues. This drug can affect liver function, so liver function tests should be performed before and during use, and discontinuation is necessary if liver function worsens. Moreover, this drug may elevate blood sugar levels, so individuals at risk for diabetes should ensure proper blood sugar management. Women who are pregnant or could become pregnant should not take this drug, and if currently taking it, must discontinue it immediately and consult their doctor. If symptoms such as dizziness or muscle pain occur, patients should inform their doctor immediately and receive necessary examinations. This drug may interact with other medications, so if any other medications are being taken, patients must inform their doctor or pharmacist. Special precautions are needed for children and the elderly, and safety has not been established in children, so it is not recommended. In case of overdose, treatment and supportive care should be provided according to symptoms, and liver and muscle conditions should be monitored. This drug should be stored out of the reach of children, and it is advisable not to transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), Stevens-Johnson syndrome (severe mucocutaneous reactions), toxic epidermal necrolysis (Lyell syndrome), skin ulcers, severe skin reactions including erythema multiforme, anaphylaxis, jaundice, fulminant hepatitis, liver failure, liver dysfunction, kidney failure, rhabdomyolysis, severe myopathy, immune-mediated necrotizing myopathy, acute kidney failure, acute severe myopathy, cerebral aneurysm, severe headache, seizures.

Mild side effects

  • Muscle pain
  • abdominal pain
  • elevated liver enzymes
  • dizziness
  • cough
  • nausea
  • diarrhea
  • joint pain
  • muscle weakness
  • musculoskeletal pain
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  • hyperkalemia
  • bronchitis
  • sinusitis
  • flushing
  • increased ALT
  • increased AST
  • weakness
  • fatigue
  • chest pain
  • peripheral edema
  • tiredness
  • fever
  • hyperglycemia
  • hypoglycemia
  • weight gain
  • loss of appetite
  • constipation
  • abdominal distension
  • indigestion
  • belching
  • pancreatitis
  • pharyngeal and laryngeal pain
  • nosebleed
  • insomnia
  • nightmares.

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly closed container to prevent air or moisture ingress and should be kept at room temperature between 1 degree and 30 degrees Celsius. This storage method helps to maintain the drug's effectiveness for a longer period.

Appearance and packaging

Appearance

White or off-white oval-shaped film-coated tablet

Package unit

30 tablets/box [(10 tablets/Alu-Alu x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.