Atoez 10/10 mg (Ezetimibe, Atorvastatin Calcium Trihydrate)

Adult dosage

This medication is to be taken once daily regardless of meals. For treatment of primary hypercholesterolemia, the dosage is between 10/10 mg and 10/80 mg daily. The initial dose is recommended to be 10/10 mg or 10/20 mg once daily. If a greater reduction in LDL cholesterol (more than 55%) is required, the initial dose of 10/40 mg daily is recommended. Dose adjustments should be made based on blood lipid levels after an interval of more than 2 weeks.

This medication helps lower blood cholesterol levels and reduce cardiovascular disease risk. Muscle issues may arise during administration, so if symptoms such as muscle pain or weakness occur, you should inform your doctor immediately. Caution should be taken in patients with a history of muscle-related diseases, poor kidney function, the elderly, or those with hypothyroidism. Liver function may be affected, so liver function tests should be conducted before starting the drug, and if any symptoms of liver dysfunction occur during treatment, tests should be repeated. This medication should not be used in patients with certain liver diseases, pregnant or potentially pregnant women, nursing mothers, and patients with lactose intolerance. There may be drug interactions, especially when taking medications that affect hepatic metabolism or those that can affect muscles, so it's important to discuss with a doctor. There may be dizziness when driving or operating machinery, so caution is advised. It is recommended to avoid or limit alcohol consumption during this medication treatment, and regular check-ups to monitor for side effects are important. In the event of overdose, there is no specific antidote; treatment and supportive care should be according to symptoms, and liver function and muscle enzyme levels should be checked. The safety and efficacy in children have not been established, and therefore it is not recommended.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion, vision abnormalities, paralysis, urination issues

Mild side effects

Muscle pain, abdominal pain, nausea, diarrhea, dizziness, fatigue, headache, joint pain, muscle weakness, musculoskeletal pain, bronchitis, sinusitis, cough, flushing, hyperkalemia, anemia, hernia, depression, bronchiolitis, tooth abscess, vestibular neuritis, bradycardia, hypotension, skin nodules, ingrown toenails, skin rash, itching, hair loss, angioedema, erythema multiforme, mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. Additionally, the drug should be kept at room temperature between 1 to 30 degrees Celsius, rather than in very hot or very cold places to maintain effectiveness.

Appearance

White to pale white, bilaterally convex oval film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP x 3]