Medication info
Etor Tablet 10/40 mg

Etor Tablet 10/40 mg

Prescription medicationTablet
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›43.4mg / 1 tablet
Manufacturer / importer
(주)휴온스
Appearance
White oblong film-coated tablet
Packaging
30 tablets/PTP [(10 tablets/PTP package (Alu-Alu) x 3)], 30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202101581 · Approved 2021.02.18 · Insurance code 670608750

Summary

Main use
Improvement of hypercholesterolemia and dyslipidemia (total cholesterol, LDL-C, etc.)
Who uses it
Adults
Adult dosage
This medication is to be taken once daily regardless of meals. For primary hypercholesterolemia, the dosage ranges from 10/10 mg to 10/80 mg per day, with an initial dose recommended at either 10/10 mg or 10/20 mg. For patients who require a greater reduction in LDL-cholesterol (more than 55%), an initial dose of 10/40 mg is recommended. After starting treatment or adjusting the dose, cholesterol levels should be checked with an interval of more than 2 weeks.

Ingredients

Manufacturer
(주)휴온스

Efficacy & effects

Improvement of hypercholesterolemia and dyslipidemia (total cholesterol, LDL-C, etc.)

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • dyslipidemia
View approved original text

This medication helps reduce total cholesterol, LDL-cholesterol, Apo B, triglyceride, and non-HDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia, and increases HDL-cholesterol, which is good cholesterol. It is also used as an adjunct therapy with other treatments for patients with homozygous familial hypercholesterolemia or when other treatments are ineffective. This medication should be used in conjunction with a diet and is employed when non-drug therapies, like limiting saturated fats and cholesterol intake, are insufficient. It is important to identify and treat other causes of dyslipidemia, such as diabetes and hypothyroidism, before therapy. Furthermore, in case of acute coronary events, lipid tests should be promptly conducted upon admission to decide on the treatment direction. This medication is effectively utilized to reduce the risk of vascular diseases associated with hypercholesterolemia.

Dosage and Administration

Adult dosage

This medication is to be taken once daily regardless of meals. For primary hypercholesterolemia, the dosage ranges from 10/10 mg to 10/80 mg per day, with an initial dose recommended at either 10/10 mg or 10/20 mg. For patients who require a greater reduction in LDL-cholesterol (more than 55%), an initial dose of 10/40 mg is recommended. After starting treatment or adjusting the dose, cholesterol levels should be checked with an interval of more than 2 weeks.

Precautions

This medication has been reported to cause a rare side effect called rhabdomyolysis, which can cause serious damage to muscles. In particular, patients presenting with severe muscle symptoms or renal issues should temporarily discontinue or stop taking this medication. Patients with an allergy to any component of this medication or those with liver issues, muscle disorders, pregnant or nursing women should not take this medication. Additionally, certain liver disease patients or those taking specific medications should also avoid using this medication. Alcoholics or patients with poor liver function and those at high risk of muscle disorders should take this medication with caution, especially elderly patients need to be careful. This medication may affect liver function, thus it is important to undergo regular liver function tests before and during treatment. Symptoms like muscle pain, abdominal pain, and increased liver enzymes are common side effects, and any abnormal symptoms should be reported to a doctor immediately. This medication may interact with other drugs, so patients should disclose any medications they are taking. Special caution is needed when taken with drugs that can cause muscle damage. Women of childbearing age should use appropriate contraceptive methods to avoid pregnancy during the use of this medication and must stop taking it immediately if pregnancy is confirmed. Symptoms like dizziness may occur, so caution is advised when driving or operating machinery. This medication is not recommended for children as its safety and efficacy have not been established for pediatric use. In the case of overdose, there is no specific antidote, so symptomatic treatment should be provided, and monitoring of liver function and muscle condition is necessary. This medication should be kept out of reach of children and should not be transferred to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, yellowing of skin or eyes (jaundice), sudden and severe headache, seizures, confusion, vision changes, paralysis, markedly reduced urine output, severe general edema with concurrent high blood pressure, severe allergic reactions, severe skin adverse reactions, respiratory issues, liver abnormalities (jaundice), severe neurological symptoms, severe edema or urination abnormalities,

Mild side effects

  • Muscle pain
  • abdominal pain
  • dizziness
  • cough
  • nausea
  • diarrhea
  • joint pain
  • muscle weakness
  • musculoskeletal pain
  • hyperkalemia
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  • bronchitis
  • sinusitis
  • flushing
  • elevated ALT
  • elevated AST
  • fatigue
  • chest pain
  • peripheral edema
  • tiredness
  • fever
  • nasopharyngitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
  • loss of appetite
  • constipation
  • abdominal bloating
  • dyspepsia
  • burping
  • pancreatitis
  • pharyngeal and laryngeal pain
  • nosebleeds
  • insomnia
  • nightmares
  • headache
  • altered perception

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air and moisture ingress and should be maintained at room temperature between 1 degree and 30 degrees. Proper storage will help retain the medication's effectiveness.

Appearance and packaging

Appearance

White oblong film-coated tablet

Package unit

30 tablets/PTP [(10 tablets/PTP package (Alu-Alu) x 3)], 30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.