Medication info

Humetob Tablets 10/40 mg

Prescription medicationTabletExpired
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›43.4mg / 1 tablet
Manufacturer / importer
(주)휴메딕스
Appearance
White oblong film-coated tablet
Packaging
PTP packaging - 30 tablets/box [(10 tablets/PTP packaging (Alu-Alu)×3)], bottle packaging - 30 tablets/bottle, bottle packaging - 100 tablets/bottle
Approval status
Expired

MFDS item code 202101578 · Approved 2021.02.18

This product's status changed to Expired on 2026.02.18. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Lipid improvement by reducing cholesterol and increasing HDL in hypercholesterolemia and dyslipidemia.
Who uses it
Adults
Adult dosage
This medication is taken once daily regardless of meals. The dosage range is 10/10mg to 10/80mg per day. As an initial dose, 10/10mg or 10/20mg per day is recommended. For patients requiring a greater reduction in LDL cholesterol, an initial dose of 10/40mg per day is recommended. After starting treatment or adjusting the dose, lipid levels should be checked at intervals of more than 2 weeks to adjust the dosage accordingly.

Ingredients

Manufacturer
(주)휴메딕스

Efficacy & effects

Lipid improvement by reducing cholesterol and increasing HDL in hypercholesterolemia and dyslipidemia.

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • elevated total cholesterol
  • elevated LDL-cholesterol
  • elevated Apo B protein
  • elevated triglycerides
  • elevated non-HDL-cholesterol
  • dyslipidemia
View approved original text

This medication helps lower total cholesterol, LDL cholesterol, Apo B protein, triglycerides, and non-HDL cholesterol levels in patients with primary hypercholesterolemia or mixed dyslipidemia, while increasing HDL cholesterol levels. In cases of homozygous familial hypercholesterolemia, it is used in combination with other lipid-lowering treatments or as an adjunctive therapy when other treatments are ineffective. This medication is utilized for the treatment of dyslipidemia in conjunction with dietary changes, and it is important to administer it considering the patient's condition and risk factors. Prior to treatment, secondary causes such as diabetes or thyroid dysfunction should be identified and managed, and blood lipid levels should be monitored regularly through blood tests if necessary. This medication is a safe and effective treatment option for improving hypercholesterolemia and related dyslipidemia.

Dosage and Administration

Adult dosage

This medication is taken once daily regardless of meals. The dosage range is 10/10mg to 10/80mg per day. As an initial dose, 10/10mg or 10/20mg per day is recommended. For patients requiring a greater reduction in LDL cholesterol, an initial dose of 10/40mg per day is recommended. After starting treatment or adjusting the dose, lipid levels should be checked at intervals of more than 2 weeks to adjust the dosage accordingly.

Precautions

This medication has been reported to cause rare serious side effects related to muscles. Patients with acute infections, hypotension, major surgery, trauma, or endocrine disorders should temporarily discontinue or stop taking this medication. Patients with allergies to this medication, severely impaired liver function, or muscle diseases, as well as pregnant or breastfeeding women, and those taking certain antiviral medications should not use this medication. Additionally, patients with genetic metabolic disorders like lactose intolerance should not take it. Patients with a history of alcohol addiction or liver disease, poor kidney function, or hypothyroidism, and elderly patients who are at higher risk of muscle-related side effects should use this medication with caution. Caution is also needed when used in combination with other lipid-lowering agents. During treatment with this medication, side effects such as muscle pain, abdominal pain, and elevated liver enzymes may occur, and if severe symptoms arise, consulting a doctor is advised. If there are signs of liver dysfunction or severe muscle problems, discontinuation of the medication may be necessary. Regular liver function tests and muscle enzyme tests should be performed before and during treatment, especially if muscle pain, weakness, or fever are present, and any such symptoms should be promptly reported to a physician. This medication may interact with various other drugs, so patients should inform their doctor or pharmacist if they are taking any other medications. Dose adjustments may be required when taken with drugs that affect liver metabolism. Women of childbearing age should employ appropriate contraception while taking this medication and should discontinue use if they become pregnant or if pregnancy is a possibility. It is also advisable for breastfeeding women to avoid taking this medication. Special caution is needed for children and the elderly, as the safety and efficacy for children have not been established. In case of overdose, there is no specific antidote, so it is important to receive treatment for symptoms and to have liver and muscle tests done. Finally, this medication should be stored out of reach of children and should not be transferred to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe allergic reactions, severe rashes accompanied by fever, blisters, skin peeling, pain of oral/eye mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough and fever, breathing problems, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice

Mild side effects

  • Muscle pain
  • abdominal pain
  • nausea
  • diarrhea
  • dizziness
  • joint pain
  • muscle weakness
  • musculoskeletal pain
  • hyperkalemia
  • bronchitis
Show 27 more
  • sinusitis
  • flushing
  • fatigue
  • chest pain
  • increased blood pressure
  • anemia
  • headache
  • pharyngitis
  • edema
  • weakness
  • malaise
  • chest discomfort
  • muscle cramps
  • sore throat
  • hives
  • skin rash
  • itching
  • hair loss
  • thrombocytopenia
  • cholestasis
  • blurred vision
  • tinnitus
  • dry skin
  • sweating
  • acne
  • muscle fatigue
  • myositis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it should be kept at room temperature between 1 and 30 degrees Celsius. This storage method preserves the medication's effectiveness and prevents degradation.

Appearance and packaging

Appearance

White oblong film-coated tablet

Package unit

PTP packaging - 30 tablets/box [(10 tablets/PTP packaging (Alu-Alu)×3)], bottle packaging - 30 tablets/bottle, bottle packaging - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.