Humetov Tablet 10/20 Milligrams

Adult dosage

This drug is taken once daily regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10mg to 10/80mg per day. A starting dosage of 10/10mg or 10/20mg per day is recommended. For patients requiring a significant reduction in LDL cholesterol (above 55%), a starting dosage of 10/40mg per day is recommended. After starting the treatment or adjusting the dosage, liver function tests should be performed after an interval of more than two weeks.

This drug has been reported to cause a rare side effect called rhabdomyolysis, which can cause severe muscle damage. If severe muscle pain or weakness occurs, notify a doctor immediately and undergo muscle-related testing. This drug should not be administered to individuals allergic to the active ingredient or other components, patients with severe liver dysfunction, patients with muscle diseases, women who are pregnant or nursing, and patients taking certain antiviral agents. Caution is required when using this drug in individuals with a history of alcohol abuse or liver disease, reduced kidney function, hypothyroidism, elderly patients, and those with other conditions at high risk for myopathy. Regular liver function tests should be performed during treatment with this drug, and if symptoms of liver dysfunction (e.g., nausea, vomiting, jaundice, etc.) occur, consult a doctor immediately. This drug may interact with other medications, so dosage adjustments or caution are necessary, especially when taken with CYP3A4 inhibitors, cyclosporine, certain antibiotics, and antiviral agents. Women taking this drug should use appropriate contraception to avoid pregnancy, and if pregnancy is confirmed, they should stop taking the drug immediately. Symptoms such as dizziness or muscle pain may occur, so caution is advised when driving or operating machinery. The safety and efficacy of this drug in children have not been established, and it is not recommended. In case of overdose, there is no specific antidote, so treatment should focus on symptomatic relief and monitoring liver function and muscle enzyme levels.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes, difficulty breathing or feeling breathless, asthma attack, respiratory abnormalities accompanied by cough+fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Muscle pain
• abdominal pain
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain
• hyperkalemia
• bronchitis
• sinusitis

This drug should be stored in a tightly closed container to prevent exposure to air and moisture. The storage temperature should be maintained between 1 to 30 degrees Celsius.

Appearance

White oblong film-coated tablet

Package unit

PTP packaging - 30 tablets/box [(10 tablets/PTP packaging (Alu-Alu)x3)], bottle packaging - 30 tablets/bottle, bottle packaging - 100 tablets/bottle