Ezetimibe 10/10 mg Tablets

Adult dosage

This medication is taken once daily, regardless of meals. The dosage range for primary hypercholesterolemia is 10/10 mg to 10/80 mg daily, with an initial dose of 10/10 mg or 10/20 mg once a day. For patients requiring a greater reduction in LDL cholesterol, an initial dose of 10/40 mg daily is recommended. The recommended dose for patients with homozygous familial hypercholesterolemia is 10/40 mg or 10.

This medication is a specific class of lipid-lowering agents and rare side effects like rhabdomyolysis, which can cause severe muscle damage, have been reported. Therefore, if severe muscle pain or weakness occurs, consult a doctor immediately. Additionally, if there are conditions that can affect renal function, such as severe infections, hypotension, or post-major surgery, it may be necessary to temporarily suspend or discontinue use of this medication. Individuals with allergies to active ingredients or components, active liver disease, unexplained liver enzyme elevation, or muscle disorders should not use this medication. Pregnant or potentially pregnant women, as well as nursing mothers, should also not take this medication. Furthermore, certain antiviral agents and patients with lactose intolerance are contraindicated for use. Caution is advised for alcoholics, individuals with impaired liver function, those with diminished renal function, patients with hypothyroidism, and the elderly, as they may have an increased risk of myopathy and may require regular monitoring. Extra caution is needed when taking this medication alongside fibrate-class drugs. During treatment, symptoms like muscle pain, fatigue, dizziness, dyspepsia, elevated liver enzymes may occur, and if any unusual symptoms appear, consult a physician. Liver function tests should be conducted regularly before and during use, and if liver damage is suspected, treatment should be stopped immediately. This medication can interact with various other drugs, so inform health professionals of any other medications being taken. Women of childbearing age should use appropriate contraception while taking this medication, and caution is required as dizziness may occur during driving or operating machinery. There is no specific antidote for overdose, and treatment needs to be symptom-oriented with supportive therapy, while monitoring liver function and muscle enzyme levels. This medication is not recommended for children as safety and efficacy have not been established. If muscle pain or weakness symptoms become severe or persistent during treatment, consult a physician, and treatment may be discontinued if necessary.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, mouth/eye mucosal pain, shortness of breath or difficulty breathing, asthma attack, respiratory anomalies accompanied by cough+fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is best stored at room temperature between 1°C and 30°C. Proper storage helps maintain the medication's effectiveness over time.

Appearance

White or pale yellow, bilaterally convex coated tablets in a capsule shape

Package unit

30 tablets/box [(10 tablets/Alu-Alu)x3]