Medication info
Adget Tablet 10/20 Milligrams

Adget Tablet 10/20 Milligrams

Prescription medicationTablet
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›21.7mg / 1 tablet
Manufacturer / importer
주식회사케이에스제약
Appearance
White, biconvex, rectangular film-coated tablet
Packaging
30 tablets/box [(10 tablets/PTP x 3)]
Approval status
Active

MFDS item code 202101568 · Approved 2021.02.18 · Insurance code 059001000

Summary

Main use
Improvement of lipids by reducing cholesterol and increasing HDL in hypercholesterolemia and dyslipidemia
Who uses it
Adults
Adult dosage
This medication is administered once daily irrespective of meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg daily. A starting dose of 10/10 mg or 10/20 mg daily is recommended. For patients requiring a greater reduction in LDL-cholesterol (more than 55%), a starting dosage of 10/40 mg daily is recommended. For homozygous familial hypercholesterolemia patients, the recommended dosage is 10/40 mg or 10/80 mg daily.

Ingredients

Manufacturer
주식회사케이에스제약

Efficacy & effects

Improvement of lipids by reducing cholesterol and increasing HDL in hypercholesterolemia and dyslipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • dyslipidemia
View approved original text

This medication aids in lowering cholesterol and triglyceride levels and increasing HDL-cholesterol in patients with primary hypercholesterolemia and mixed dyslipidemia. It can be used in conjunction with or as an alternative to other treatments, particularly for patients with homozygous familial hypercholesterolemia. For patients at high risk of atherosclerotic vascular disease due to hypercholesterolemia, this drug can be used alongside dietary therapy to improve serum lipid levels. However, research on various types of dyslipidemia is limited, making it crucial to identify and manage other secondary causes prior to treatment. This medication should be used in addition to a diet that restricts saturated fat and cholesterol, with personalized treatment based on the patient's risk factors. In conclusion, this medication is used for managing dyslipidemia and improving blood lipid levels.

Dosage and Administration

Adult dosage

This medication is administered once daily irrespective of meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg daily. A starting dose of 10/10 mg or 10/20 mg daily is recommended. For patients requiring a greater reduction in LDL-cholesterol (more than 55%), a starting dosage of 10/40 mg daily is recommended. For homozygous familial hypercholesterolemia patients, the recommended dosage is 10/40 mg or 10/80 mg daily.

Precautions

This medication may rarely cause rhabdomyolysis, which can lead to kidney problems due to muscle tissue destruction. Therefore, if severe muscle pain or weakness occurs, it is important to consult a physician immediately. Patients at high risk of myopathy should have blood tests before and during treatment to monitor muscle damage. This drug may affect liver function; therefore, patients with liver disease or elevated liver enzyme levels should not take it. Pregnant women, women who may become pregnant, and breastfeeding women should not use this medication. Caution is advised for patients who consume alcohol heavily, have a history of liver disease, are elderly, or have impaired kidney function. When taken with other medications, the risk of side effects from this medication may increase due to interactions, so consultation with a physician or pharmacist is essential. If muscle pain, dizziness, abdominal pain, or nausea occurs during treatment, medical staff should be informed immediately, and tests should be conducted if necessary. Regular liver function tests and blood tests are advisable during the course of this medication. Safety in children and adolescents has not been established, so it is not recommended for them. This medication may cause dizziness while driving or operating machinery, so caution is necessary. When storing this medication, keep it out of reach of children and do not transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, breathlessness or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), severe and sudden fatigue, sudden and severe headaches, lightning-like headaches, seizures, confusion of consciousness, visual disturbances, paralysis, and changes in urination.

Mild side effects

  • Muscle pain
  • abdominal pain
  • elevated liver enzymes
  • dizziness
  • cough
  • nausea
  • diarrhea
  • joint pain
  • muscle weakness
  • hyperkalemia
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  • bronchitis
  • sinusitis
  • flushing
  • fatigue
  • malaise
  • chest pain
  • fever
  • vomiting
  • dyspepsia
  • constipation
  • headache
  • throat and laryngeal pain
  • nosebleed
  • nightmares
  • sensory disturbances
  • sensory loss
  • taste disturbances
  • amnesia
  • peripheral neuropathy
  • musculoskeletal pain
  • muscle cramps
  • joint swelling
  • back pain
  • neck pain
  • muscle fatigue
  • and rupture.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius. This helps to safely maintain the medication's effectiveness.

Appearance and packaging

Appearance

White, biconvex, rectangular film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.