Zentor Tablet 10/40 Milligrams (Ezetimibe, Atorvastatin Calcium Trihydrate)

Adult dosage

This medication is administered once a day without regard to meals. For primary hypercholesterolemia, the dosage range is from 10/10 mg to 10/80 mg daily, with an initial recommended dose of 10/10 mg or 10/20 mg once daily. For patients requiring a reduction in LDL cholesterol of more than 55%, an initial dose of 10/40 mg once daily is recommended. After dosing or adjusting the dosage, lipids in the blood should be checked after intervals of at least 2 weeks.

This medication poses a risk of muscle abnormalities, so if severe muscle pain or weakness occurs, it should be reported to a physician immediately. Particularly in cases of severe infection or surgery, the use of this medication may need to be temporarily halted. Patients who have allergies to any components of this medication, or who have liver or muscle diseases, should not take this medication. Women who are pregnant or may become pregnant, as well as those who are breastfeeding, should not use this medication. Patients with impaired liver function or those who consume a lot of alcohol should have their liver function tested periodically while taking this medication. This medication may interact with other drugs, so if currently taking any other medications, it is essential to inform a physician or pharmacist. Caution is especially needed when taken with certain antibiotics, antifungals, antivirals, and immunosuppressants, as this may increase the risk of muscle damage. Regular liver function tests and muscle-related tests should be conducted while taking this medicine, and any unusual symptoms should be discussed with healthcare professionals immediately. Symptoms such as dizziness or drowsiness may occur, so caution is advised when driving or operating machinery. Special care is needed for children and the elderly, as the safety and efficacy of this medication are often not established, requiring adherence to healthcare professionals' guidance. There is no specific antidote for overdose, so immediate medical attention should be sought based on symptoms. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rashes with high fever, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, lightning-like headaches, seizures, confusion of consciousness, vision disturbances, paralysis, urination.

Mild side effects

• Muscle pain
• abdominal pain
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain
• dizziness
• fatigue
• headache

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained between 1 and 30 degrees Celsius to prolong the efficacy of the medication.

Appearance

White or whitish oval film-coated tablets

Package unit

30 tablets/box [(10 tablets/Alu-Alu×3)]