Ezetimibe/Atorvastatin 10/40 Milligrams

Adult dosage

This drug is taken once daily without regard to meals. For primary hypercholesterolemia, it is administered in a dosage range of 10/10mg to 10/80mg per day; the initial recommended dose is 10/10mg or 10/20mg per day. For patients requiring a significant reduction in LDL cholesterol, the initial dose of 10/40mg per day is recommended. After starting treatment or adjusting dosage, lipid levels should be checked more than 2 weeks apart.

This drug is helpful in lowering blood cholesterol levels to reduce the risk of cardiovascular diseases. When taking this drug, serious muscle abnormalities may occur; thus, patients should inform their doctor immediately if they experience symptoms such as muscle pain, cramps, or weakness. In particular, if severe muscle pain is accompanied by fever, immediate medical attention is needed, and blood tests can be conducted to check for muscle damage. Since it may affect liver function, liver function tests should be conducted before starting this drug, and if any abnormal liver function symptoms occur during treatment, patients should consult healthcare professionals. Patients with severe liver disease or persistent unexplained elevations in liver enzyme levels should not take this drug. This drug should not be administered to patients with certain liver diseases, muscle diseases, pregnant women or women who may become pregnant, lactating women, and patients taking certain other medications. Patients who consume excessive alcohol or have a history of liver disease, patients with reduced kidney function, patients with hypothyroidism, elderly patients, etc., require caution when taking this drug. This drug may interact with various other medications, so if a patient is taking other medications, they must inform their healthcare providers, especially when combined with certain antibiotics, antiviral agents, antifungal agents, immunosuppressants, antihypertensives, hypoglycemic agents, or fibrate medications. Women of childbearing age should use appropriate contraceptive methods to avoid pregnancy during the use of this drug and should stop taking it immediately if pregnancy is confirmed. Symptoms like dizziness or headache may occur, so caution is needed when driving or operating machinery. In case of overdose, there is no specific antidote; therefore, appropriate treatment should be provided based on symptoms, and liver function and muscle damage should be monitored. The safety and efficacy of this drug in children have not been established, so it is not recommended for pediatric use. It is important to regularly check liver function and muscle status through doctor's appointments and blood tests during the course of this medication.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, pain in the oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue throughout the body, sudden and severe headache, lightning-like headache, seizures, confusion, visual disturbances, paralysis, urination difficulty

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• constipation
• diarrhea
• headache
• fatigue

This drug should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain the storage temperature between 1 and 30 degrees Celsius.

Appearance

White or whitish oval film-coated tablets

Package unit

30 tablets/box [10 tablets/Alu-Alu x 3]